Effects of regular exercise on the liver function tests of male subjects in college of health sciences, Nnamdi Azikiwe University, Nnewi campus, Anambra state, Nigeria.
Journal Title: INTERNATIONAL JOURNAL OF CURRENT RESEARCH IN MEDICAL SCIENCES - Year 2018, Vol 4, Issue 3
Abstract
Background: Frequent and regular exercise boosts the immune system and prevents the disease of affluence and depression while promoting positive self-esteem. There is paucity of information on this study in Nnewi hence the research. Objectives: This study investigated the effects of regular exercise on the liver function tests of apparently healthy male subjects in College of Health Sciences, Nnamdi Azikiwe University, Nnewi campus, Anambra State, Nigeria. Methods: A total of 60 subjects were randomly recruited into the pre and post experimental design study. Thereafter, they were divided into two (2) groups consisting of 30 soccer players in each group. They were rested for a period of two weeks and thereafter subjected to vigorous exercise(30 minutes of football playing three times a week for 3 weeks). Five (5) mls each of baseline and post exercise (day21) samples were collected into a plain container for the estimation of biochemical parameters alkaline phosphatase (ALP), aspartate aminotransferase (AST), alanine transaminase (ALT), The gamma-glutamyl transferase (GGT) respectively using colorimetric methods. Data obtained were analyzed using unpaired Student t-test and Pearson correlation. Results: The mean serum activity of ALT(9.13±4.84 Vs6.08±2.96); ALP (260.23±21.50 Vs 179.51±110.28) and GGT(44.64±34.84 Vs 29.59±14.10) were significantly increased in the studied subjects post exercise when compared with the pre exercise stage (P < 0.05) whereas the mean serum AST activity did not differ significantly in the subjects post exercise when compared with the pre exercise stage (P < 0.05). Conclusion: This study showed that vigorous exercise increases ALT, ALP and GGT enzyme activity but do not have significant effect on AST. Therefore, vigorous exercise should be performed with caution to avoid exercise-induced hepatic cell damage
Authors and Affiliations
Ihim Augustine Chinedu1 , Iloesie Stephen Chima1 , *Ogbodo Emmanuel Chukwuemeka1, , Oguaka Victor Nwabunwanne2 , Meludu Samuel Chinedu1,2 .
Keywords
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- EP ID EP563369
- DOI 10.22192/ijcrms.2018.04.03.010
- Views 106
- Downloads 0
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