Effects of systemic toxicity produced by fluoride: in vivo study
Journal Title: Stomatos - Year 2018, Vol 24, Issue 47
Abstract
This study sought to verify possible systemic changes caused by fluoride administered at different concentrations. An animal model was used in which 60 rattus norvegicus were randomly divided into 4 groups, with three test groups receiving fluoridated water at the different concentrations (0.7 ppm F, 1.2 ppm F and 2, 0 ppm F), and a control group receiving distilled water. A histomorphological analysis was performed by light microscopy after the dissection of the following rat organs: the large intestine (duodenum), the kidney and the liver. The results obtained after the comparative descriptive evaluation of the study groups showed morphological changes in all the test groups, concluding that the fluoride administered at these concentrations could be toxic.
Authors and Affiliations
Alessandra Dutra da Silva, Andreza Lapis Schinelli, Carolina Coradini Abascal, Marcia Kijner, Sabrina Pozatti Moure, Paulo Oliva de Borba
Keywords
Related Articles
- EP ID EP536492
- DOI -
- Views 76
- Downloads 0
The influence of caregivers qualification in oral health of dependent elders in Santa Maria/RS, Brazil
Objective: This study aimed to evaluate the knowledge of professional caregivers of dependent elderly. Methods: The study population consisted (n=24) and dependent elders (n=157) in a nursing home in Santa Maria, Brazil....
In vitro comparative study on the efficacy of home and in-office techniques
The purpose of this study is to determine the most effective bleaching technique of vital teeth, considering the existence of different techniques. Results obtained from one in-office bleaching agent were compared to tho...
Combined orthognathic surgery and prosthetic treatment for class III skeletal malocclusion
This clinical report discusses the case of a partially edentulous patient with class III skeletal malocclusion, suffering from poor masticatory function and esthetic appearance caused by severe anteroposterior discrepanc...
PREVALENCE OF ABUTMENT TEETH FOR CONVENTIONAL FIXED PROSTHESES IN A BRAZILIAN SUBPOPULATION
The purpose of this cross-sectional study was to evaluate the prevalence of abutment teeth for conventional fixed prostheses in a Brazilian subpopulation. Panoramic radiographs for a total of 1,401 patients taken f...
Evaluation of caries management protocols in children 0-3 years of age based on risk
Introduction: Early Childhood Caries is a disease of high prevalence and severity that accompanies children in the rst years of life, necessitating, therefore, approaches based on clinical protocols. Facing primary care...