Effects of Vitamins in Augmentation of Malaria Treatment: A review
Journal Title: Asian Pacific Journal of Health Sciences - Year 2016, Vol 3, Issue 4
Abstract
Malaria continues to cause significant morbidity and mortality in several settings in the tropical regions of the world despite the availability of efficacious and potent antimalarial drugs. This has led to an increased interest in and evaluation of micronutrients which are well known to have antioxidant effects. However, the interaction of micronutrients with malaria is not well characterized and there are conflicting results on their impact. This review examines, in particular, the relationship between vitamin supplements and malaria treatment. Data indicate that concurrent use of vitamins with antimalarial drugs may either accelerate the potency of the drugs or antagonize their effects. Also, evidence do exist that deficiencies of some of these supplements may protect, exacerbate or have both effects on malaria parasitemia, depending on the settings. Therefore, it is safe to speculate that the use of antimalarial drugs alongside vitamins should be approached with caution, in order to not undermine the potency of the drug and to assure effective disease treatment.
Authors and Affiliations
Dr. Joshua B. Owolabi
Keywords
Related Articles
- EP ID EP524506
- DOI 10.21276/apjhs.2016.3.4.6
- Views 147
- Downloads 0
Pattern of comorbidities in psoriasis patients from western India and the relation between disease severity and systemic comoridities: cross sectional study at a tertiary care centre
Background: Various studies have shown association of much physical and psychosocial comorbidity with psoriasis. Aims & Objectives: To note pattern of various comorbidities in psoriasis patients and the association of sy...
Oral squamous cell carcinoma of tongue in a young patient- a rare case report and review of literature
Oral Squamous cell carcinoma is the most common malignant neoplasm affecting oral cavity, generally seen in individuals over 50 years of age and rarely before 40 years of age. As OSCC is rare in younger group, it may be...
Abducens nerve palsy and diplopia concomitant with psa nerve haematoma secondry to posterior superior alveolar nerve block
Complications in local anesthesia practice have been described in literature in terms of their local and systemic manifestations. These complications arise to a variable degree. It is important for a practicing clinician...
Etiology of vaginal infections and antimicrobial resistance pattern of aerobic bacterial isolates in women of reproductive age group attending a tertiary care hospital
Background: The vaginal flora is a complicated environment containing dozens of microbiological species in variable quantities and relative proportions. Many women with vaginitis may remain undiagnosed and such forms of...
To Study the Etiology and Predicting Scores of Patients with acute on chronic liver failure
Aim: To study the aetiology, precipitating insults of patients presenting with acute on chronic liver failure and predictors of mortality of acute chronic liver failure. Methods: The prospective study was carried out in...