EFFECTS OF X-RADIATION ON THE SALIVARY COMPOSITIONS
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2017, Vol 4, Issue 8
Abstract
Background: Saliva plays an important role in maintaining healthy teeth. There are many factors that may affect saliva compositions furthermore the X-radiation. Knowledge about the effects of irradiation on the saliva remains of great interest to many researchers. The aim of this study: To observe the effect of radiation on the most salivary organic and inorganic constituents in patients with head and neck malignancies treated by fractionated radiotherapy. Materials and Methods: This study included eighty male subjects between the ages 30-45 years, forty patients with head and neck cancers treated by fractionated radiotherapy for three months and forty others were healthy volunteers. The total dose is 40 to 44 Gy, given in five fractions per week with a daily target dose of 1.8-2.0 Gy per day. Evaluation of most organic and inorganic components in saliva were achieved for all individuals following radiotherapy. Total protein, albumin /IgM, IgA, IgG/ amylase, calcium, magnesium, phosphate concentrations of saliva were evaluated using Biuret test, turbidimetery and spectrophotometry respectively. Results: The statically analyses showed significant increase in total protein and albumin levels in radio-treated patient group when compared to control group and a significant decrease in salivary IgA and IgM levels in radio-treated patient group but there is a non-significant increase in salivary IgG level was observed when compared to control group. The statically analyses showed a significant reduction in amylase levels was observed in radio-treated patients when compared to control group. The statically analysis also showed no significant differences in Calcium, Phosphate and Magnesium levels in the patient with radio-therapy when compared with control group. Conclusion: The study concluded that the X-radiation affect the most composition of saliva and changes some of their proportions.
Authors and Affiliations
Dr. Hussein Haleem Jasim
Keywords
Related Articles
- EP ID EP630469
- DOI -
- Views 140
- Downloads 0
SUBJECTIVE ORAL HEALTH PERCEPTION AND CHEWING DISCOMFORT DEPENDING ON ORAL HEALTH CARE BEHAVIOR
In order to provide the baseline data for reducing chewing discomfort and improving the level of subjective oral health perception by grasping the correlation among oral health care behavior, subjective oral health statu...
ABO BLOOD TYPES OF BABCOCK UNIVERSITY STUDENTS, NIGERIA AND THEIR LINK WITH HELICOBACTER PYLORIINFECTION
Five millilitres (5ml) of venous whole blood was collected from one hundred and eighty three students made up of 93(50.8%) male and 90(49.2%) female students of Babcock University, Ilishan Remo randomly selected across v...
COMMON CAUSES OF RISKY PREGNANCY AMONG PREGNANT WOMEN IN IRAQ
Introduction: Pregnancy factors are those that affect women's pregnancy and pregnancy requirements and its important because their consequences have a higher likelihood of complications or health problems during pregnanc...
ASSOCIATION BETWEEN MICRORNA 196A-2 POLYMORPHISM AND SERUM TYROSINASE LEVEL AND ITS INFLUENCE ON TREATMENT OF VITILIGO PATIENTS
Background: MicroRNAs (miRNAs) are discovered family of endogenous, noncoding RNA molecules. miRNAs modulate the gene expression post-transcriptionally by binding to complementary sequences in the coding or 3' untranslat...
THE ASSESSMENT OF KNOWLEDGE, ATTITUDES AND PRACTICES REGARDING DIET AND EXERCISE AMONG TYPE 2 DIABETES MELLITUS PATIENTS IN DERNA, LIBYA
Introduction: Diabetes mellitus is one of the prevalent chronic diseases that can be managed by life style modification. Disease can be controlled effectively by providing proper knowledge and awareness regarding disease...