Efficacy and Safety of Addition of Teneligliptin to Type 2 Diabetes Patients Inadequately Controlled with Triple Drug Treatment with Glimepride + Metformin + Voglibose
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 3
Abstract
Type 2 diabetes is a significant health problem and its prevalence is increasing globally. There are several challenges to the management of type 2 diabetes in the Indian population. A single-center study evaluated the efficacy and safety of addition of teneligliptin 20 mg/day to type 2 diabetes patients inadequately controlled with triple drug treatment with glimepride + metformin + voglibose. Overall, 81 were prescribed teneligliptin in addition to triple drug treatment. At study end, 62.12% patients achieved HbA1c levels <7%. Patients reported only mild/transient adverse effects during the study period. It was concluded that addition of teneligliptin to triple drug therapy with glimepride + metformin + voglibose is efficacious to attain HbA1c below 7% in diabetes patients inadequately controlled with the triple therapy. It is also a safe drug since the adverse effects reported following the addition of teneligliptin were mild/transient.
Authors and Affiliations
Dr SR Patnaik
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