Efficacy and Safety of Fat-Derived Autologous Expanded Mesenchymal Stem Cell Therapy for the Management of Musculoskeletal Conditions: A 5-Year Experience
Journal Title: Journal of Orthopaedic Science and Research - Year 2022, Vol 3, Issue 3
Abstract
This editorial addresses the efficacy of single or repeated fat-derived autologous expanded Mesenchymal Stem Cell (MSC) therapy for orthopaedic conditions, specifically degenerative and injury-related joint and soft tissue disorders. Over the last five years, we have tried MSC therapy for peripheral large and small joints in several hundreds of clients. Our process starts with rheumatologic consultation at the regenerative clinic to select suitable candidates for MSC therapy. We rule out active cancer and pregnancy. Next, the surgical team performs the fat harvesting process under local anaesthesia. We send the sample to our sterile biologic lab for culture-expansion of the MSCs to many millions based on the area (s) involved and the severity of the condition. The cells remain frozen until the MSCs implantation time.
Authors and Affiliations
Hassan Mubark
Keywords
Related Articles
- EP ID EP708936
- DOI https://doi.org/10.46889/JOSR.2022.3301
- Views 34
- Downloads 0
Four-Dimensional CT Assessment of the Transverse Carpal Ligament Attachments-A Pilot Study
Introduction: The wrist is a complex joint, and static imaging techniques may not capture subtle kinematic abnormalities. Four-dimensional (4D) CT presents an alternative method of assessing the dynamic movement of the T...
Syndrome of Contractures and Deformities (SofCD): Dysplasia of Hips, Varus Deformity of Shanks, Wry Neck, So-Called Idiopathic Scoliosis Causes Clinic Prophylaxis Therapy
In the article we present one of two main etiopathological groups of pathology of locomotor system. The health of the adults very often depends on the effectiveness of prophylaxis and proper treatment of disorders in the...
Pes Equinus in Healthy Children and Adolescents
Background: Pes equinus is associated with various pathologies and, generally speaking, appears frequently in healthy children and adolescents. The object of this study is to diagnose and treat pes equinus and, where pos...
The Role of Obesity on Cast Index and Secondary Intervention in Pediatric Forearm Fractures
Background: Pediatric forearm fractures are common, and the majority are treated with closed reduction and immobilization. Additionally, the incidence of pediatric obesity is rising. Cast index is a useful metric to as...
Arthroscopic Bursal Acromial Reconstruction for Paraplegic Basketball Player: A Case Report
In paraplegic patients, rotator cuff tears are known to be common. Even after rotator cuff repair, the frequent use of crutches or wheelchairs can lead to high stress on the shoulder, increasing the risk of re-tear. This...