Efficacy and safety of insulin pump treatment in adult T1DM patients – influence of age and social environment
Journal Title: Annals of Agricultural and Environmental Medicine - Year 2012, Vol 19, Issue 3
Abstract
Introduction and objective. Continuous subcutaneous insulin infusion (CSII) via personal insulin pump is a valuable therapeutic tool in T1DM patients. However, adherence to recommended CSII- related behaviours may be of concern to young adults with intensive, variable daily activities (students, young professionals). The aim of this observational study was to estimate treatment outcomes in young adult patients with T1DM, and compare them with older individuals.Materials and methods. Overall, 140 adults with T1DM on CSII were examined, divided into 2 subgroups: 77 patients younger than 26 years of age (mean 20.6 years) and 63 older subjects (mean 39.0). We compared the glycaemic control in both groups of T1DM subjects and analyzed treatment attitudes to identify potentially modifiable behaviours influencing the efficacy of the treatment.Results. The younger individuals were characterized by significantly worse treatment outcomes, compared to the older ones: the mean HbA1c levels were 7.6 ± 1.3% and 6.9±1.3% (p=0.00001), while the mean glucose levels based on glucometer downloads were 161±33.6 mg/dL and 136±21.8 mg/dL (p=0.00001), respectively. The frequency of self-monitoring of blood glucose (SMBG) was lower in younger individuals (5.3±2.1 vs. 7.0±2.8 daily, p=0.0005, respectively); they were also less frequently used advanced pump functions, e.g. the bolus calculator (48% vs. 67% users, p=0.0014, respectively).Conclusions. The efficacy of CSII treatment observed in young T1DM adults was worse than in older patients. The reason for this phenomenon remains unclear, it may be due simply to age-dependend behaviours, to social environment, or both.
Authors and Affiliations
Małgorzata Grzanka, Bartłomiej Matejko, Katarzyna Cyganek, Elżbieta Kozek, Maciej Małecki, Tomasz Klupa
Keywords
Related Articles
- EP ID EP80512
- DOI -
- Views 115
- Downloads 0
Comparison of indicators of the use of insulin and oral diabetes medication in a Polish population of patients in urban and rural areas in the years 2008, 2011 and 2012
introduction. Diabetes is one of the 10 most important chronic diseases in the world. According to the data of the International Diabetes Federation, in Poland 9% of the population between the ages of 20–79 suffer from d...
Exposure and respiratory health in farming in temperate zones--a review of the literature.
To review studies in farming populations from temperate zones focusing on: (1) exposure to dust, bacteria, moulds, endotoxin, and ammonia, (2) sensitisation to common airborne allergens, (3) prevalence, incidence and ris...
Pulmonary embolism associated with oral contraceptive use – Case report
A 25-year-old female patient with a history of oral contraceptive use was admitted to hospital because of exertional dyspnoea, palpitations, chest discomfort and weakness. Since the clinical presentation was suggestive o...
Progress in the molecular methods for the detection and genetic characterization of Cryptosporidium in water samples.
Cryptosporidium, the protozoan parasite, has several transmission routes, including anthroponotic and zoonotic transmission, as well as the foodborne way, but mainly by water. The oocysts, the resistant stage produced by...
Identification of host blood-meal sources and Borrelia in field-collected Ixodes ricinus ticks in north-western Poland
Forest animals play fundamental roles in the maintenance of [i]Ixodes ricinus[/i] and [i]Borrelia[/i] species in the forest biotope. To identify the forest vertebrate species that are host for I. ricinus and for the reco...