Efficacy and safety of Olopatadine versus Azelastine in allergic conjunctivitis at a Government Medical College, Betiah, Bihar- A prospective study
Journal Title: Journal of Advanced Medical and Dental Sciences Research - Year 2017, Vol 5, Issue 8
Abstract
Background: Allergic eye diseases influences around one-fifth of the total populace. Olopatadine hydrochloride and Azelastine hydrochloride are double acting selective H1 receptor antagonist with mast-cell stabilizing property. This investigation was embraced to evaluate the adequacy and wellbeing of olopatadine hydrochloride 0.1% and Azelastine hydrochloride 0.05% in allergic conjunctivitis. Materials and Methods: 80 patients with the sign (hyperemia) and side effects of allergic conjunctivitis (i.e., tearing, itching and photophobia) were randomized (stratifying by age and sex) 1:1 to get either 0.1% with olopatadine hydrochloride (OHCL) and Azelastine 0.05% eye drops BD for 15 days (one drop in each eye each 12 h). Signs and manifestations were scored prior and then afterward 2 weeks of medication while side effects were scored 30 min and 2 weeks after treatment start. A composite score of signs and indications was characterized by including all measures of signs and manifestations and after that subtracting the week 2 entirety from the pretreatment aggregate. Result: Both medications decreased signs and indications of allergic conjunctivitis at 2 weeks from gauge. The treatment with 0.1% OHCL was more powerful contrasted with the azelastine gathering. Essentially, the scores of ocular congestion, foreign body sensation, tearing, erythema and chemosis likewise demonstrated bigger decrease in the olopatadine treated patients. Conclusion: The aftereffects of this single-dosage contemplate recommend that olopatadine is better than epinastine regarding smothering ocular itching and hyperemia. Additionally contemplates are expected to affirm these discoveries, in real-life settings.
Authors and Affiliations
Shawana Barkat, Anil Sinha
Keywords
Related Articles
- EP ID EP560984
- DOI -
- Views 117
- Downloads 0
Comparative Evaluation of Levels of Vascular Endothelial Growth Factors in Aqueous Humor in Diabetic and Non-Diabetic Patients
Background: It is assumed, therefore, that the profile of the aqueous humor can afford useful information relating to inflammatory processes in the eyes. In patients with progressive diabetic retinopathy (PDR), neo-vascu...
Efficacy of Antibiotic Prophylaxis after Removal of Impacted Mandibular Third Molar
Background: Removal of impacted teeth is a very common surgical procedure performed by dentists. The importance of the patient’s discomfort from the surgical removal of third molar impaction is the post-operative complic...
Prosthetic Rehabilitation of Hypohidrotic Ectodermal Dysplasia: A Case Report
Ectodermal dysplasia is a rare group of inherited conditions in which two or more ectodermally derived anatomical structures fail to develop or partially develop. Hypohidrotic ectodermal dysplasia is most common type in...
Assessing the Medical Health Statistics of Patients in a Dental Institute
Objective: The study was planned for assessing the medical complications of patients in a dental OPD (Outpatient department). Methods: A total of 1260 patients were included in the study further divided into different ag...
Assessment of the Outcome of Bipolar Hip Arthroplasty in Young Adults as Treatment of Avascular Necrosis of Femoral Head
Background: Avascular necrosis (AVN) of the femoral head is now recognised as a major musculo-skeletal problem mostly affecting the young people in their productive years of life. It causes pathologic death of osteocytes...