Efficacy and safety of subconjuctival bevacizumab injection in the management of pterygium
Journal Title: Indian Journal of Clinical and Experimental Ophthalmology - Year 2018, Vol 4, Issue 2
Abstract
Purpose To assess the efficacy and safety of subconjunctival bevacizumab in the management of grade II and III pterygiumMaterials and Methods Cases of pterygium with no other ocular abnormality and with no systemic disorders were subjected to anterior segment photography and graded Ten cases of grade III pterygium and eleven cases of grade II pterygium were administered subconjunctival intralesional injection of 25mg01ml of bevacizumab Anterior segment photographs were taken on day 7 day 28 and day 90 along with complete ocular examination and general physical examination The pterygium vascularity size and thickness were assessed keeping note of any adverse effects ophthalmic or otherwise An evaluation of the symptoms before injection and at day 90 was also doneResults There was statistically significant improvement in the grade color intensity size of pterygium and symptoms of patients There was a decrease in symptoms of redness itching watering and irritationOf the 10 cases with Grade III on enrollment 08 80 had shown a decrease in vascularity with half of them graded as II and the remaining half as grade IOf the 11 cases of Grade II pterygium at baseline 05 45 cases changed to grade I by day 90Conclusion This study revealed that the subconjunctival injection of bevacizumab was found to be useful in reduction of symptoms of patients with grade III II pterygium with no local or systemic adverse effectsKeywords Bevacizumab Pterygium Subconjuctival Treatment
Authors and Affiliations
Meenakshi Pathania, VS Gurunadh, MA Khan
Keywords
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- EP ID EP474209
- DOI 10.18231/2395-1451.2018.0046
- Views 90
- Downloads 0
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