Efficacy and Tolerability of an Advance Face Night Cream in Reducing Facial Pigmentation and Wrinkles in Women
Journal Title: Journal of Dermatology Research - Year 2024, Vol 5, Issue 2
Abstract
Background: The efficacy and tolerance of an Advance Face Night Cream in reducing facial pigmentation and wrinkles in women was evaluated. Methods: This was a monocentric, single-group, comparative, open-label study involving healthy adult women with mild to-moderate wrinkles and at least one pigmented spot on the face. The Advance Face Night Cream was to be applied every night before bedtime along with sunscreen lotion (with sun protection factor [SPF] 50) during the day. Evaluations included clinical examination and grading of wrinkles in the crow’s feet area, nasolabial region, forehead and under the eyes. Skin lightening and skin hydration effects along with subjective efficacy were also evaluated. Results: Thirty-three women completed the study (mean age: 44.03±5.41 years). A significant decrease in the mean score of wrinkles in the crow’s feet area (7.5%; p=0.004) and on the forehead and under-eye region (12.5%; p=0.001) was noted at 45 days. The 3-dimensional imaging revealed a significant decrease in the mean overall size of wrinkles after 21 and 45 days (10.0% and 9.0%; p=0.002 and p=0.003, respectively) and the mean width of wrinkles (3.5% and 4.4%; p=0.007 and p=0.001, respectively). Comparable benefits in skin radiance, color and hydration were noted at both 21 and 45 days. Other benefits included improved skin moisture, reduced visible pigmentation and wrinkles and improved overall skin appearance. Conclusion: The topical application of Advance Face Night Cream and the appropriate usage of sunscreen lotion with SPF 50 led to a significant reduction in fine lines and the overall size and width of facial wrinkles in 3 and 6 weeks. The cream could significantly hydrate the skin, brighten the skin tone and lighten the skin color of the pigmented area in 3 weeks. No adverse events were reported by any participant during the study.
Authors and Affiliations
Rajiv Joshi, Dyotona Sen, Sanjay Choudhary
Keywords
Related Articles
- EP ID EP741623
- DOI https://doi.org/10.46889/JDR.2024.5209
- Views 58
- Downloads 0
Flattened Nose Revealing Syphilitic Aortitis
Flattened nose also called syphilis nose is a deformation of the nose due to the destruction of the cartilage of the nasal septum: the lower segment of the nose collapses, undergoes recoil and retract, becoming embedded...
Sugar Consumption and Acne: Unravelling the Complex Sugar-Skin Relationship in the Adolescent Population
Aim: To look into the complex relationship between adolescent acne severity and sugar consumption. Objectives: This project is based on five objectives, as follows: Completely examine the association between Sugar...
Chemokine Ligand-Receptor Axes for Therapeutic Targeting During Skin Regeneration
Chemokines and their cognate receptor interactions regulate the balance between pro-inflammatory and anti-inflammatory signals to support the physiological functions of the skin. Chemokines also regulate the process of a...
Atypical Fibroxanthoma of the Scalp in a Young Woman: A Case Report
Atypical fibroxanthoma, is an uncommon tumor of fibrohistiocytic mesenchymal origin that occurs on the sun-damaged skin of elderly men. The clinical presentation is a solitary cutaneous nodule. The diagnosis is made by...
A Case of Pseudochromohidrosis Cured with Oral Erythromycin and Topical Clindamycin
Apocrine chromohidrosis and eccrine pseudochromohidrosis are both rare skin presentations. In case of former patient presents with coloured sweats in apocrine distributions usually axilla, breast etc., while later pres...