Efficacy of 0.03% tacrolimus eye ointment in refractive vernal kerato-conjuctivitis with corneal involvement
Journal Title: Medpulse International Journal of Ophthalmology - Year 2018, Vol 8, Issue 2
Abstract
Aim: To study clinical efficacy of 0.03% tacrolimus eye ointment in refractive vernal keratoconjunctivitis (VKC) will) cornel involvement and proliferate lesion. Methods: Prospective observational study of 106 pts aged 7- 18yr (I2±5yrs). After taking history, total 8 clinical clinical signs and 5 symptoms were noted and graded. Patients were started with 0.03% tacrolimus eye ointment twice daily and followed up for 6 months. Results: Statistically significant improvement was seen in patients with conical involvement and giant papillary lesions (p<0.001).48 patients (4:3%) showed improvement after 1 month. After 6 months, 100 patients (95%) showed improvement in signs and symptoms. Only side effect observed was burning sensation (3 patients) that was relieved with lubricating drops. Conclusion: 0.03% Tacrolimus eye ointment was safe and effective in VKC cases resistant to anti-allergic/steroid/cyclosporine eye drop especially with proliferative lesions and corneal involvement.
Authors and Affiliations
Kedar Nemivant, Aabha Bhalerao
Keywords
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- EP ID EP460641
- DOI 10.26611/1009822
- Views 114
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