Efficacy of dexamethasone in prevention of trismus in mandibular third molar surgery
Journal Title: Scholars Academic Journal of Pharmacy - Year 2016, Vol 5, Issue 9
Abstract
Abstract:Corticosteroids (dexamethasone and methylprednisolone) have been reported to control postoperative outcome when given preoperatively. The aim of study is to evaluate efficacy of dexamethasone in prevention of trismus in mandibular third molar surgery. In a randomized double-blind and clinical trial study, 54 patients referred to Department of Oral and MaxillofacialSurgery with age range of 18-26 years. In case group, 20mg oral dexamethasone 2 hours before and 2 hours after surgery was used and in control group, 20mg multivitamintablet 2 hours before and 2 hours after surgery was used. How and maximum mouth opening were checked for every patients before surgery, 2 hours and 48 hours after surgery. The mouth opening size was statistically significant after 2 hours and 48 hours in case group compared with control group that the mouth opening size was more in case group compared with control group. The results showed that oral dexamethasone reduced trismus of third molar surgery and probably lower dose of dexamethasone has faster efficacy on incisal opening after surgery. Keywords:Third molar surgery, dexamethasone, trismus.
Authors and Affiliations
Hamid Reza Mozaffari, Mohammad Ramezanian, Masoud Sadeghi, Roohollah Sharifi, Shabnam Sadeghilar
Keywords
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