Efficacy of Hbv Vaccine on Healthy and Leukemic Children in Libya
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 5
Abstract
Hepatitis B is one of the most important causes of acute and chronic hepatitis world over. Children with malignant disease are at an especially high risk for developing hepatitis B virus (HBV) infection. The increasing potential for the cure of childhood malignant diseases emphasizes the need for a method of reducing hepatitis and its sequelae in these children. The efficacy of this HBV vaccine among Leukemic children in Tripoli Medical center (TMC), Tripoli, Libya is the aim of this study. Study was conducted at TMC, Tripoli, Libya in 2016 with 399 healthy (255) and leukemic (144) children. All cases were treated with HBV vaccine of 3 doses. Venous blood collected and examined for AntiHBST. Result showed that male leukemic children were more than healthy one. 4 to 6 years old male children have observed more in this study. Regarding AntiHBST, no differences have seen in healthy and leukemic children, no gender variation in its responses and the responses were gradually decreased with increase of ages. It is concluded that, the HBV vaccination has not shown much role in controlling the HBV infection in Luekemic children and booster dose may be required.
Authors and Affiliations
Aboubaker Saleh Alasga, Eman Rajab Markus, Kamal Faraj Zaed
Keywords
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- EP ID EP373893
- DOI 10.9790/0853-1705013740.
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