Efficacy of macular hole surgery with inverted internal limiting membrane flap technique and air tamponade

Journal Title: Eye Science (Yanke Xuebao) - Year 2025, Vol 40, Issue 4

Abstract

[Objective] To assess the efficacy of the inverted internal limiting membrane (ILM) flap technique with air tamponade for macular holes (MHs). [Methods] A retrospective analysis was conducted on 71 patients (71 eyes) who underwent inverted ILM flap surgery combined with air tamponade for macular holes at Zhongshan Ophthalmic Center from 2016 to 2019. Patients were positioned face down for 1-3 days postoperatively and followed up for more than 6 months. OCT was used to determine the closure rate of macular holes, and the best corrected visual acuity (BCVA) before and after surgery was compared. The MAIA microperimeter was used to assess the average macular sensitivity, macular integrity index, and fixation stability P1 and P2 before and after surgery. [Results] Of the total 71 eyes, 91.5% achieved complete MH closure. The best corrected visual acuity (BCVA) significantly improved before and after surgery (P<0.001), average macular sensitivity significantly increased (P<0.000 1), macular integrity index significantly decreased (P<0.000 1),and fixation stability P1 (P<0.000 1) and P2 (P<0.001) both significantly improved. [Conclusions] Inverted ILM flap technique combined with air tamponade provides an effective approach for the management of MHs. The air tamponade should be considered as the preferred in MH surgeries, reducing the discomfort caused by prolonged face-down positioning. Parameters in microperimetry can serve as good indicators for assessing the recovery of macular structure and function.

Authors and Affiliations

Jing CHEN, Qi ZHANG, Xiujuan ZHAO, Lin LU

Keywords

Related Articles

Cataract surgery in a patient with anterior megalophthalmos: a case report and literature review

Anterior megalophthalmos is a rare congenital enlargement of the anterior segment, characterized by bilateral nonprogressive megalocornea (diameter ≥12.5 mm), extremely deep anterior chamber, normal or moderate thinning...

NMPA premarket application experience for a computer aided diagnosis software using fundus images of diabetic retinopathy

Based on the NMPA premarket application through two and a half years for the computer aided diagnosis software using fundus images of diabetic retinopathy, which is an innovative medical device of Shanghai EagleVision Me...

Research progress on gene therapy for ABCA4-related stargardt disease

Stargardt disease (STGD1, OMIM#248200) is the most common hereditary macular dystrophy, caused by mutations in the ABCA4 gene, and is an autosomal recessive inherited disorder. The disease typically manifests in late chi...

Effects of caffeine intake on tear film dynamics in healthy adults

[Objective:] To investigate the effects of high caffeine intake in a short period on tear film dynamics in healthy adults. [Methods:] The participants were 12 healthy adults (20–30 years old) with no history of ocular su...

Research progress of organelle degradation and its mechanisms during lens development

During terminal differentiation of lens fiber cells, nuclei and other organelles experience programmed elimination. This process is essential for the maintenance of lens transparency. However, the mechanisms underlying l...

Download PDF file
  • EP ID EP767356
  • DOI 10.12419/24110604
  • Views 12
  • Downloads 0

How To Cite

Jing CHEN, Qi ZHANG, Xiujuan ZHAO, Lin LU (2025). Efficacy of macular hole surgery with inverted internal limiting membrane flap technique and air tamponade. Eye Science (Yanke Xuebao), 40(4), -. https://europub.co.uk/articles/-A-767356