Efficacy of optimal pulse technology in the treatment of meibomian gland dysfunction
Journal Title: Eye Science (Yanke Xuebao) - Year 2020, Vol 35, Issue 2
Abstract
[Objective:] To evaluate the efficacy of optimal pulse technology (OPT) in treating meibomian gland dysfunction (MGD). [Methods:] A total of 32 (64 eyes) MGD patients were randomly divided into the experimental group (16 eyes) and the control group (16 eyes). Patients in the experimental group were treated with OPT and those in the control group were given with deproteinized calf blood extract eye drops combined with eyelid massage. Ocular surface disease index (OSDI) score, lipid layer grading, non-invasive Keratograph tear break-up time (NIKBUT), and non-invasive tear meniscus height (NITMH), cornea fluorescein staining (CFS), meibum quality score (MQS), meibomian gland expressibility score (MGES) and eyelid margin capillary distribution score of patients in the experimental and control groups before and after treatment for 50 days were evaluated, respectively. [Results:] In the experimental group, OSDI score was decreased, lipid layer grading was increased, and NIKBUT, CFS, MQS, MGES and capillary distribution were significantly improved after treatment compared with those before treatment (all P<0.05). In the control group, OSDI score, lipid layer grading, NIKBUT, CFS and MGES were significantly after treatment (all P<0.05). There was no significant difference in MQS and capillary distribution score before and after treatment (both P>0.05). After treatment, NITMH in two groups showed no significant improvement (P>0.05). After treatment, the improvement of OSDI score, lipid layer grading, NIKBUT, MQS and capillary distribution score in the experimental group were better than those in the control (all P<0.05). [Conclusion:] OPT treatment can effectively improve the function of MGD, enhance the steady state of tear film and mitigate subjective dry eye symptoms.
Authors and Affiliations
Saisai ZHANG, Yanshuang YAN, Xilan TANG, Hui DAI, Yaolei DU
Keywords
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- EP ID EP763398
- DOI 10.3978/j.issn.1000-4432.2020.04.06
- Views 24
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