Efficacy of Recombinant Interferon-α-2b Application in Children with Virus-Induced Bronchial Asthma Phenotype
Journal Title: Здоров`я дитини - Year 2013, Vol 6, Issue 49
Abstract
The paper presents the results of the study of the efficacy of recombinant interferon α-2b use in children with bronchial asthma, who often suffer from acute respiratory viral infection (ARVI). It is established that under the influence of recombinant interferon-α-2b use for prolonged scheme, the content of INF-γ increases, the concentration of IgE decreases, with the tendency to normalization of the oxidant-antioxidant status. The clinical criteria of recombinant interferon-α-2b efficcacy are 2.4-fold decrease in ARVI incidence, 3.3-fold reduction in the frequency of bronchial asthma against ARVI, which has a positive effect on the clinical course of bronchial asthma. The period of remission in patients increased up to 4–6 months, duration of seizure period decreased.
Authors and Affiliations
O. V. Fofanova
Keywords
Related Articles
- EP ID EP236377
- DOI -
- Views 66
- Downloads 0
Digestive Diseases in the Structure of Somatic Pathology in Adolescents with Nontoxic Diffuse Goiter
145 girls and 177 boys aged 10–17 years were examined to determine a place of digestive diseases in the structure of somatic pathology in adolescents with nontoxic diffuse goiter. Thyroid ultrasound has been carried out,...
Features of the course of broncho-obstructive syndrome in young children depending on the level of vitamin D
Background. Diseases of the respiratory tract, including broncho-obstructive syndrome (BOS), are common pathology in childhood. It is known that the incidence and severity of respiratory diseases correlates with the leve...
About exanthema subitum in children
The article describes etiopathogenesis, clinical picture, diagnosis, management and prognosis of exanthema subitum (ES). The disease occurs in nearly all infants and is not well-known in the general medical community. Ex...
Hereditary Fructose Intolerance
Hereditary fructose intolerance, the prevalence of which is 1 : 20,000 population, is diagnosed much less frequently than is found in child and adult populations. Presented pathology is caused by a deficiency in ferment...
The impact of vitamin D3 supplementation on the course of acute obstructive bronchitis in young children
Background. Acute obstructive bronchitis (AOB) ranks second among the respiratory diseases in children. In recent years, the results of clinical studies demonstrate a correlation between the low level of vitamin D (VD) a...