Efficacy of Red cell distribution width (RDW) as a screening test for diagnosing children with Iron Deficiency anaemia
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2014, Vol 2, Issue 6
Abstract
The Objective of present study is to evaluate the efficacy of Red Cell Distribution Width as a screening test for diagnosing children with Iron Deficiency anaemia. Prospective study method and Statistical methods were used. Sensitivity, specificity, positive predictive value, negative predictive value and Receiver Operating Characteristics (ROC) were studied. Out of 97 patients, Females were 32 ( 38 % ), Males 65 (62 % ).Maximum number of patients were in the age group of 1 – 6 years 39 ( 40.2 % ). Out of 97 cases, 67 (68%) were found to have iron deficiency anaemia and 31 (32% ) were non iron deficient anaemia. In this study, severe anaemia was found in 3 cases ( 3.1%), moderate anaemia in 26 cases (26.5%) and mild anaemia in 68 cases (70.4%). The mean standard deviation for RDW in iron deficient cases was 13.68±2.88. Sensitivity, specificity, positive predictive and negative predictive value were obtained using Receiver Operating Characteristics (ROC) curves with a cut off RDW of 14 and 13.With cut off 14, sensitivity was 47%,, specificity 75 %, positive predictive 60%, and negative predictive value 63%, False positive 25% and false negative 53%. With cut off 13, sensitivity was 64%,, specificity 58 %,, positive predictive 56%, and negative predictive value 67%, False positive 42% and false negative 36%. RDW may not be useful as a screening test and other studies evaluating iron stores in the body like serum iron, serum ferritin, iron binding capacity and serum transferrin saturation may still be needed for appropriate diagnosis of iron deficiency anaemia. Keywords: Iron Deficiency anaemia, RDW, ROC.
Authors and Affiliations
Chithambaram Nagalingam Saroja, Shailaja Alapaty, Mrs Mini Jeyan
Keywords
Related Articles
- EP ID EP379031
- DOI -
- Views 61
- Downloads 0
Evaluation of Serum Acid Phosphatase Level in the Lesions of Prostate Gland and its Role as Tumour Marker in Advanced Carcinoma of Prostate and its Correlation with Histopathology
Abstract: Acid phosphatase (ACP) enzyme, first demonstrated in the urine 1925, was found to be much more prevalent in male than in female. It was shown that prostatic tissue contains this enzyme in high concentration. El...
A Clinicopathological study of Psoriasis
Papulosquamous group of skin lesions have certain common clinical presentations and lead to confusion in diagnosis. We undertook this study to analyze the histomorphological findings of psoriasis, the most common and imp...
A Study of Role of Wound Drain in the Open Mesh Repair of Incisional Hernia
Abstract: A sum of 50 patients with incisional hernia were included in this study. The clinical features, symptomatology, investigations, operative findings, postoperative wound complications and length of hospital stay...
A Study of Port Site Infection Following Laparoscopic Cholecystectomy in a Tertiary Care Hospital of Tripura
Port site infection is a bothersome complication which undermines the benefits of minimal access surgery. Despite the advances in the field of antimicrobial agents, sterilization techniques, surgical techniques, operatin...
Clinical Study of Sutika-Dashmoola Kwatha in well being of Sutika
It is the woman who procreates children and propagates the human species. Dharma (righteousness), Artha (wealth), Lakshmi (auspiciousness), and Loka (the entire universe) are represented in every woman”. Ayurveda regards...