Efficacy of Vacuum-Assisted Closure Therapy versus Conventional Povidone Iodine Dressing in the Management of Diabetic Foot Ulcers: A Randomized Control Trial
Journal Title: International Journal of Health Sciences and Research - Year 2017, Vol 7, Issue 5
Abstract
Objective: To equate the effectiveness of vacuum-assisted closure therapy (VACT) with conventional povidone iodine dressing (CTPID)in the management of diabetic foot ulcer (DFU). Methods: It was a 14-day study in which a total of 60 patients were divided into two equal groups (n = 30) using computer-generated random numbers. Group A and group B received VACT and CTPID treatment for DFU, respectively. A sub atmospheric pressure of 100–125 mmHg was applied to the wound in VACT group and povidone iodine-soaked gauze was used for dressing in CTPID group. The wounds were assessed on day 0, 5 and 14 of the treatment for the mean area of ulcer. Culture sensitivity test for bacterial growth was performed on day 0 and 14 to determine the infection status by disc diffusion method. Result: At the end of the study (day 14),mean surface area of the ulcer treated with VACT and CTPID was reduced from 11.21cm2 to 8.6cm2 and 12.24cm2 to 11.30 cm2, respectively (p = 0.029). Two patients of group A and eight patients of group B showed positive growth for gram-positive cocci such as Staphylococcus aureus, and gram-negative organisms such as E.coli, Proteus, Klebsiella, Pseudomonas and Enterococcus on day 14 of repeat culture (p = 0.038). Interpretation: VACT was found to be more effective in treating DFU with respect to healing rate and time when compared to the conventional povidone iodine dressing.
Authors and Affiliations
Dr. B. M. Kajagar
Keywords
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