EFFICIENCY OF BIOFLAVONOID QUERCETIN AND RNA-CONTAINING DRUG SODIUM NUCLEINAT IN COMPLEX TREATMENT OF PATIENTS WITH MYOCARDIAL INFARCTION AND FUNCTIONAL LIVER DISORDERS
Journal Title: Health Problems of Civilization - Year 2017, Vol 11, Issue 4
Abstract
<B>Background</B>. The study has shown that functional liver disorders develop in patients with MI, which requires correction. <B>Material and methods</B>. The study involved 149 patients with acute MI. All examinations were repeated several times on the 1, 14 and 28 day of the treatment. <B>Results</B>. The patients with functional liver disorders have a higher incidence of epistenocardial pericarditis, arrhythmia and systolic dysfunction. They are characterised by highly activated lipid peroxidation and immunological disorders. A combined therapy with quercetin resulted in improving hemodynamics and reducing the manifestations of liver dysfunction. RNA-containing drug significantly improved the immune status and reduced signs of immuno-inflammatory syndromes. <B>Conclusions</B>. 1.In patients with MI and functional liver disorders, the primary pathological process is characterised by significant violations of systolic and diastolic function of the heart, more frequent development of complications, activation of lipid peroxidation and secondary immunodeficiency. 2. The inclusion of bioflavonoid quercetin in the treatment of patients with MI helps to restore the antioxidant defence system, improve myocardial contractile function and reduce clinical laboratory manifestations of cytolytic and cholestatic syndromes in patients due to antioxidant and membrane stabilizing properties of the drug. 3. The usage of the RNA-containing drug Nuclex improves immune reactivity, reduces symptoms of expressed mesenchymal-inflammatory and necro-resorptive syndromes in patients with MI and functional liver disorders.
Authors and Affiliations
Mykola Shved, Olena Prokopovych, Sofiya Lypovetska, Svitlana Heryak, Yaroslav Kitsak
Keywords
Related Articles
- EP ID EP321682
- DOI 10.5114/hpc.2017.71891
- Views 48
- Downloads 0
ANALYSIS OF THE HEART RATE VARIABILITY FOR WOMEN, SPECIALIZING IN RACE WALKING, THROUGHOUT THE MENSTRUAL CYCLE
The article presents the results of studies of the heart rate variability for women, specializing in race walking, at different phases of the menstrual cycle (MC). The results of spectral analysis of heart rate indicate...
VARIATIONS IN MORPHOLOGY OF LUMBAR SPINAL CANAL IN DEGENERATIVE DISCOPATHY
Background. Lumbar spine, due to the large range of motion, is exposed to frequent occurrence of intervertebral disc disease. Discopathy initiates a series of changes as a result of a change in the morphology of the spin...
State of knowledge (concerning the alcohol dependence) of the patients undergoing a therapy in the Department of Twenty-Four-Hour Addiction Treatment in Łuków
The aim of research was to determine the effects of therapy and its influence on the way people addicted to alcohol perceive alcoholism. This work contains the basic knowledge concerning the core of alcoholism, its stages...
THE ANALYSIS OF SPECIFIC IMMUNE RESPONSE FOR BORRELIA BURGDORFERI ACCORDING TO IN VIVO ANTIGENS IN REGARD TO SYMPTOMS SUBJECTIVELY PERCEIVED BY FORESTERS
The aim of our this work was analysis of speciic immune response for B. burgdorferi according to in vivo antigens in regard to symptoms subjectively perceived by foresters, in 2009 and 2012. Material and methods: study...
THE PRESENCE OF ANTI-BORRELIA BURGDORFERI ANTIBODIES IN PERSON WITH SUSPECTED LYME DISEASE
Background: Lyme disease is a multi-organ disease caused by spirochetes, Borrelia burgdorferi sensu lato, transmitted by Ixodes, with its clinical picture including involvement of the skin, joints, nervous system and hea...