Efficiency of EBUS-TBNA for diagnosing benign and malignant lymphadenopathy
Journal Title: Journal of Acute Disease - Year 2018, Vol 7, Issue 5
Abstract
Objective: To determine whether endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) can rapidly distinguish among lung cancer, tuberculosis and sarcodosis, and to explore its sensitivity and specificity. Methods: Clinical data of patients with enlarged mediastinal or hilar lymphadenopathy who underwent EBUS-TBNA at our hospital between September 1, 2012 and June 30, 2015 for were retrospectively analyzed. The sensitivity, specificity, positive predictive value, and negative predicted value [including 95% confidence interval (CI)] were calculated.. Results: A total of 299 lymph nodes from 201 patients underwent EBUS-TBNA were selected and no serious complications occurred. EBUS-TBNA showed a sensitivity of 87.9% (124/141) (95% CI: 81%–92%), a specificity of 100.0% (124/124) (95% CI: 97%–100%), and a negative predicted value of 41.3% (95% CI: 23%–61%) in the detection of lung cancer. The sensitivity and specificity of diagnosis of mediastinal tuberculosis lymphadenitis were 72.4% (21/29) (95% CI: 53%–87%) and 100.0% (95% CI: 82%–100%); while sensitivity and specificity of diagnosis of sarcoidosis were 71.4% (5/7) (95% CI: 29%–96%) and 100.0% (95% CI: 91%–100%). Conclusions: The sensitivity and specificity of EBUS-TBNA do not significantly differ for a diagnosis of lung cancer versus tuberculosis or sarcodosis.
Authors and Affiliations
Yang-Li Liu, Xiao-Ran Liu, Hui Li, Feng-Jia Chen, Huai Liao, Can-Mao Xie
Keywords
Related Articles
- EP ID EP429829
- DOI 10.4103/2221-6189.244169
- Views 129
- Downloads 0
Analysis of the disease spectra in patients seeking emergency medical treatment in Haikou, China
Objective: To explore the characteristics of medical emergency disease spectra in Emergency Department of Haikou, China; and to provide clinical data for emergent disease treatment as well as emergency department personn...
Acute middle ear Aspergillus niger infection in a patient with StevensJohnson syndrome: a case report
Rationale: Stevens-Johnson syndrome is a disorder mostly attributed to drug use, which can cause different skin problems. Patient concerns: A 31-year-old woman presented with severe pain and pounding in the left ear. Dia...
Clinical investigation results of cave trapped victims in acute phase after being rescued: Data on case of 2018 cave crisis in Thailand
No
Effect of self-management program on health status of elderly patients with heart failure: a single-blind, randomized clinical trial
Objective: To determine the effect of self-management program on the health status of elderly patients with heart failure. Methods: The present study was a single-blind, randomized clinical trial, and conducted on 90 pat...
Biomarkers in acute brain trauma: A narrative review
Biomarkers have been used to diagnose, prognose, evaluate, and identify the severity and outcomes in traumatic brain injury (TBI) patients. This study explored if it is possible to predict the outcome of TBI patients by...