Electrochemotherapy increases local control after incomplete excision of a recurring penile fibrosarcoma in a stallion
Journal Title: Open Veterinary Journal - Year 2016, Vol 6, Issue 3
Abstract
An eleven-year-old stallion was referred for adjuvant treatment of an incompletely excised, recurring penile fibrosarcoma. The horse was bright, alert and responsive with a 15 x 12 cm ulcerated lesion on the ventral side of the penis. The lesion was the tumor bed of an incompletely excised fibrosarcoma. After complete staging procedures, the owner elected to treat the horse with electrochemotherapy (ECT) using cisplatin as chemotherapy agent. Two sessions of ECT were performed at two-week intervals using local cisplatin followed by trains of biphasic electric pulses applied using different electrodes until complete coverage of the area was achieved. The treatment was well tolerated, and the patient is still disease free after 12 months. ECT resulted in improved local control and should be considered among the available adjuvant treatments in equines carrying soft tissue tumors.
Authors and Affiliations
E. P. Spugnini| Biopulse S.r.l., Naples, Italy, C. Bolaffio| Equivet Roma Hospital, Rome, Italy, L. Scacco| Equivet Roma Hospital, Rome, Italy, A. Baldi| Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, Second University of Naples, Italy
Keywords
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- EP ID EP9391
- DOI http://dx.doi.org/10.4314/ovj.v6i3.12
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