Electrophysiological Changes in Uncontrolled Type-2 Diabetic People with Peripheral Neuropathy
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 7
Abstract
Introduction: Diabetes mellitus the incidence of which is very high in our nation and presenting as a serious health problem. Some of its serious complications are retinopathy, neuropathy, nephropathy and vascular problems. Among these peripheral neuropathy is reaching 60-70% of the diabetic population especially if it is uncontrolled and of longer duration. Majority of cases of neuropathy can be delayed with judicious control of hyperglycemia and early diagnosis of neuropathy. Nerve conduction studies are of great help in the diagnosis and treatment of neuropathy. Materials And Methods: After the judicious elimination of possible other types of neuropathies, the study group consists of 30 subjects with uncontrolled diabetes mellitus type -2 between the age groups of 40-55yrs, of both sexes. Study period is from June 2014 to June 2015.All the cases are from an endocrinology center present in Visakhapatnam. All these patients were subjected to electrophysiological studies in the neurophysiolology laboratory at Visakhapatnam. Instrument used is NeuroPerfect. The nerves selected for the study are: Motor- median nerve, ulnar nerve in the upper limb, lateral poplitial and posterior tibial in lower limb. Sensory- median nerve, ulnar nerve in upper limb and sural nerve in the lower limb. Results: Motor Changes: The distal latencies are increased in ulnar of the upper limb and lateral popliteal in the lower limb. Amplitude is decreased in ulnar and posterior tibial nerves. Slowing of (NCV) was prominent in all the cases.”F” wave was normal. Sensory Changes: The Amplitude was extremely low in the sural nerve. Amplitude and NCV were moderately decreased in median and ulnar nerves. Conclusion: In our study diabetic neuropathy most commonly manifests as symmetrical peripheral polyneuropathy, the most common manifestation being symmetrical sensory loss in the distal lower extremities and motor deficits. Upper extremity involvement is less common progressing in the duration of the disease
Authors and Affiliations
Dr. Subbarao Goteti
Keywords
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