Elevated Neutrophil-to-Lymphocyte Ratio May Be Associated with Overactive Bladder Patients
Journal Title: European Archives of Medical Research - Year 2020, Vol 36, Issue 2
Abstract
Objective: Overactive bladder (OAB) may be interrelated with chronic inflammation. The aim of this study was to assess the role of neutrophillymphocyte ratio (NLR) levels in men and women with OAB symptoms. Methods: Between January 2017 and February 2018, a total of 157 subjects (77 OAB patients and 80 controls) were included in the study. The subjects divided into two groups. Group 1=OAB patients and group 2=normal controls. Patients with active urinary tract infections, previous pelvic surgery or neurogenic patients were excluded. The enrolled both patients and control group were questioned using the 8-item OAB questionnaire (OAB-v8) complete blood count and serum C-reactive protein (CRP) levels were measured in the first visit. Results: The mean NLR was 1.73±0.67 in patients and 1.48±0.75 in control groups (p<0.001). The NLR and CRP levels were both statistically significant higher in OAB patient group (p=0.03 for CRP and p=0.001 for NLR). There was positive correlation between OAB-v8 scores and NLR (p<0.001, r=0.215) Conclusion: High serum NLR levels were observed in OAB patients. Our results support the association between chronic inflammations of the bladder in OAB patients.
Authors and Affiliations
Mehmet Gökhan Çulha, Recep Burak Değirmentepe, Sait Özbir, Samir Agalarov, Muammer Bozkurt, Erkan Merder, Fatih Altunrende, Alper Ötünçtemur
Keywords
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- EP ID EP685998
- DOI 10.4274/eamr.galenos.2019.80775
- Views 121
- Downloads 0
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