Elevated Neutrophil-to-Lymphocyte Ratio May Be Associated with Overactive Bladder Patients

Journal Title: European Archives of Medical Research - Year 2020, Vol 36, Issue 2

Abstract

Objective: Overactive bladder (OAB) may be interrelated with chronic inflammation. The aim of this study was to assess the role of neutrophillymphocyte ratio (NLR) levels in men and women with OAB symptoms. Methods: Between January 2017 and February 2018, a total of 157 subjects (77 OAB patients and 80 controls) were included in the study. The subjects divided into two groups. Group 1=OAB patients and group 2=normal controls. Patients with active urinary tract infections, previous pelvic surgery or neurogenic patients were excluded. The enrolled both patients and control group were questioned using the 8-item OAB questionnaire (OAB-v8) complete blood count and serum C-reactive protein (CRP) levels were measured in the first visit. Results: The mean NLR was 1.73±0.67 in patients and 1.48±0.75 in control groups (p<0.001). The NLR and CRP levels were both statistically significant higher in OAB patient group (p=0.03 for CRP and p=0.001 for NLR). There was positive correlation between OAB-v8 scores and NLR (p<0.001, r=0.215) Conclusion: High serum NLR levels were observed in OAB patients. Our results support the association between chronic inflammations of the bladder in OAB patients.

Authors and Affiliations

Mehmet Gökhan Çulha, Recep Burak Değirmentepe, Sait Özbir, Samir Agalarov, Muammer Bozkurt, Erkan Merder, Fatih Altunrende, Alper Ötünçtemur

Keywords

Related Articles

Comparison of Bipolar TURP and Monopolar TURP Patients Who Underwent Surgery Due to Benign Prostatic Hyperplasia

Objective: Benign prostatic hyperplasia (BPH) is the one of the most common disease in the world. Transurethral resection of prostate (TURP) is the gold standard procedure in BPH surgery. So TURP methods are important. T...

Effect of Epidermal Growth Factor on Osteosarcoma Cell Proliferation and Bcl-2 Gene Expression

Objective: The aim of this study was to investigate the effects of epidermal growth factor (EGF) on osteosarcoma cell proliferation and Bcl-2 expression. Methods: In this study, MTT test was first applied to determine t...

Rare Extrapulmonary Tuberculosis in Immunocompetent Adults: Experience of a Tertiary Hospital

Objective: Tuberculosis (TB) is an infection that can involve all tissues and organs. Although pulmonary TB (PTB) is more common, extrapulmonary TB (EPTB) is still a major clinical problem. The incidence of EPTB is 35.1%...

Endo-first Approach for Peripheral Vascular Disease: The First Fifty Cases of a New Clinic

Objective: In recent years, endovascular and hybrid therapies have come to the forefront in the treatment of peripheral arterial disease (PAD) instead of open surgical treatment. In this study, we aimed to present the re...

Evaluation of Hysteroscopy in Infertile Patients

Objective: The aim of this study was to evaluate the hysteroscopy results in infertile patients and to compare the clinical pregnancy, live birth and abortion rates between patients with uterine cavity abnormalities trea...

Download PDF file
  • EP ID EP685998
  • DOI 10.4274/eamr.galenos.2019.80775
  • Views 110
  • Downloads 0

How To Cite

Mehmet Gökhan Çulha, Recep Burak Değirmentepe, Sait Özbir, Samir Agalarov, Muammer Bozkurt, Erkan Merder, Fatih Altunrende, Alper Ötünçtemur (2020). Elevated Neutrophil-to-Lymphocyte Ratio May Be Associated with Overactive Bladder Patients. European Archives of Medical Research, 36(2), -. https://europub.co.uk/articles/-A-685998