Emergence of drug resistance of Acinetobacter at tertiary care hospital
Journal Title: International Journal of Research in Pharmacology & Pharmacotherapeutics (IJRPP) - Year 2015, Vol 4, Issue 3
Abstract
BACKGROUND & OBJECTIVE Acinetobacter, although saprophytic, the emergence and spread of Acinetobacter in hospital environment is a major area of concern. . It has been associated with a wide variety of illnesses in hospitalized patients, especially patients in the intensive care units. These infections are often difficult to treat, because of the widespread antibiotic resistance. This study is conducted to know the prevalence and drug resistant pattern of Acinetobacter in tertiary care hospital. MATERIAL & METHODS 950 isolates of Acinetobacter were obtained from various clinical samples, and subjected to identification by different biochemical tests and antibiotic susceptibility testing by disc diffusion testing by Kirby Baurer method. RESULT Out of 950 isolates of Acinetobacter, 82% were Acinetobacter. calcoaceticus baumannii complex remained 18% were other Acinetobacter spp. Acinetobacter isolates were resistant to important groups of antibiotics tested, including amikacin (50%), gentamycin (65%), tobramycin (38%), ceftriaxone (92%), ceftazidime (80%), cefepime (88%), ampicillin-sulbactum (44%), piperacillin-tazobactum (38%),ciprofloxacin (81%) levofloxacin(82%), imipenem (10%) and trimethoprim-sulfamethoxazole (65%), meropenem (15%), polymixin B (2.2%), colistin (2%). CONCLUSION Early detection of MDR Acinetobacter and infection control practices are the best defense against these organisms. Rational use of antimicrobials is an important aspect to delay the emergence of XDR and PDR Acinetobacter spp.
Authors and Affiliations
Jethwa DK
Keywords
Related Articles
- EP ID EP410907
- DOI -
- Views 108
- Downloads 0
Evaluation of pattern, predictability, severity and preventability of adverse drug reactions in the department of psychiatry at a tertiary care hospital in bengaluru – a five years experience
Objective Psychotropics are known to cause number of adverse drug reactions (ADRs) which often results in either nonadherence or discontinuation of therapy. Present study aimed to analyze the pattern as well as causalit...
A study on colposcopic directed biopsy in early detection of premalignant and malignant lesions of cervix
The aim of the study is to determine the outcome of women referred for Colposcopy and directed biopsy with abnormal pap smears and smears showing persistent inflammation. Cervical cancer is a significant health problem w...
An overview of Depression and its Pharmacotherapy
Depression is a very common mental health disorder, increasing with the socioeconomic and medical condition. Patients experience different feelings, depending upon the severity, frequency, and duration of symptoms. If l...
Evaluation of in vitro anticancer activity of cucumis sativus linn leaves
Qualitative analysis of the extract revealed that it contains Glycosides, Alkaloids, Tannins, Proteins and amino acids, Phytosterol and Steriods, Terpenoids, Saponins. The anticancer activity of ethanolic extract of Cuc...
Epidemiological study of diabetes mellitus DM among different ethnic segments of population in Pakistan: A nationwide ethnographapical study
Introduction Diabetes mellitus is one of the leading causes of morbidity and mortality worldwide. It has been estimated that the number of people with diabetes mellitus will greatly increase in the upcoming years. This...