Emotional disturbances and unfavorable events after myocardial infarction with ST-segment elevation: a «case — control» study
Journal Title: Український терапевтичний журнал - Year 2019, Vol 0, Issue 3
Abstract
A large volume of papers gives considerations of the effects of anxiety and depression on the onset and exacerbation of the course of cardiovascular diseases, however the majority of them was devoted to the conditions at their clinical stage and required the involvement of a psychiatrists in the investigational team. The nature of association of psychical and somatic state remains insufficiently studied, but it becomes increasingly actual. Objective — to investigate the association of the subclinical level of anxiety, depression and stress with the unfavorable events after 6 month observation after STEMI. Materials and methods. The «casecontrol» study involved 144 patients, from them 72 patients were included in the «case» group (STEMI patients with subclinical emotional disturbances) and 72 subjected referred to the «control» group, STEMI patients comparable with age, sex and cardiovascular risk factors. Emotional disturbances were assessed with DASS 21 questionnaire. The observations lasted for 6 months. The combined endpoint was assessed: the onset of heart failure in accordance with current recommendations [18], post-infarctional angina, cardiovascular death, hospitalization due to cardiovascular reasons. Results and discussion. The chance of cardiac end point cumulation before 6 months after STEMI was in 2.5 times higher in the group with emotional disturbances compared to the group without disorders, 95 % CI 1.12—5.33, р = 0.034. The development of heart failure significantly contributed to the cardiac end point development, OR 3.75, 95 % CI 1.12—10.61; р = 0.039. Conclusions. DASS 21 questionnaire can be sued as a reliable tool for diagnosing of emotional disturbances and possible prediction of the cardiovascular events.
Authors and Affiliations
O. V. Petyunina, M. P. Kopytsya
Diseases of civilization: liver and polymorphic metabolic continuum
The paper presents considerations of the role of liver in the lipoproteins’ exchange and possibilities of correlation of its disturbances within metabolic syndrome as the most typical manifestation of polymorbid patholog...
Peculiarities of the heart failure course in patients with non-toxic goiter: clinical aspects
Objective — to investigate peculiarities of the heart failure (HF) course in patients with non-toxic goiter (NG). Materials and methods. Examinations involved 222 patients with HF (with previous myocardial infarction (MI...
Life and destiny of the creator of domestic insulin V. M. Kogan—Yasnyi (to the 130th anniversary of the birth)
-
Hypolipidemic efficacy of probiotic Lactobacillus plantarum in patients with coronary heart disease
Objective — to evaluate the lipidlowering effect of probiotics Lactobacillus plantarum by comparing the efficacy of the combination of this probiotic and simvastatin with simvastatin monotherapy in patients with coronar...
Metabolic disorders in patients with arterial hypertension with concomitant obesity
Objective — further investigation of the pathogenetic triggers of arterial hypertension with concomitant obesity. Materials and methods. Examinations involved 111 patients with arterial hypertension (AH) with concomitant...