Enantioselective Michael Addition of Diethyl Malonate on Substituted Chalcone Catalysed by Nickel-Sparteine Complex
Journal Title: Organic Chemistry: Current Research - Year 2017, Vol 6, Issue 1
Abstract
A series of transition metal with Sparteine a novel chiral catalyst was facilely synthesized, all of which contain a chiral Sparteine unit as a bidentate ligand. These bidentate chiral auxiliaries were found to be an efficient chiral catalyst in nickel-mediated, enantioselective Michael addition of Diethyl malonate to substituted chalcone. The corresponding adducts were obtained in good yields (80-91%) under simple and clean reaction condition.
Authors and Affiliations
Manojkumar U Chopade
Keywords
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- EP ID EP358237
- DOI 10.4172/2161-0401.1000178
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