Endocrine analysis in patients with hirsutism
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2016, Vol 4, Issue 10
Abstract
The aim of the study is to co-relate various laboratory and imaging profiles in patients with hirsutism. Hirsutism is defined in this study by using Modified Ferriman-Gallwey score ≥ 8 (mFG). 30 female patients between 15-50 years of age were included in the study. Detailed history and clinical examination were conducted for each patient followed by various endocrinal tests like FBS, PPBS, FSH, LH, Free and Total Testosterone, DHEAS, Fasting insulin, Thyroid Profile, 17-hydroxyprogesterone and Prolactin. Radio diagnosis studies including ultrasound, CT scan were also carried on selected patients. Mean age of presentation of hirsutism was found to be 20-29 years of age in our study. Upper lip was the most common site involved. Irregular menses and hair loss were the most common associated chief complaints noted. Obesity had a significant correlation with severity of hirsutism. Idiopathic hirsutism was the most common diagnosis found in our study followed closely by polycystic ovarian syndrome. We detected one case of Non classical congenital adrenal hyperplasia and no cases of adrenal or ovarian tumors. Serum testosterone and LH/FSH ratio were found to be elevated with PCOS group as compared to IH group. Obesity had a strong relation with severity of hirsutism independent of other parameters. Fasting blood sugar, serum testosterone, TSH and Fasting insulin levels had no correlation with severity of hirsutism. Keywords: Hirsutism, endocrinal profile, Modified Ferriman-Gallwey (mFG).
Authors and Affiliations
Dr. Aarti Shah, Dr. Som Lakhani, Dr. Uzzaif Mansuri, Dr. Sukun Patel
Keywords
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