Endogenic Intoxication and Kidney
Journal Title: International Journal of Pediatric Research - Year 2016, Vol 2, Issue 2
Abstract
The following information about the endogenous intoxication in children (from 2 up to 17 y.o.) with nephrological diseases was presented. Endogenous intoxication as multisystemic pathological condition occurs as the result of action on the organism of toxic substances of endogenous or exogenous origin. It is characterized by the following: a) violation of the barrier function of the organism against toxins, b) violation of transport mechanisms of toxic substances to the organs of their transformation and/or excretion. Endogenous intoxication leads to disruption of the structure, function, and antigenic properties of protein molecules that can cause severe chronic renal disease.
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