ENDOPHYTIC FUNGI: TREASURE FOR ANTI-CANCEROUS COMPOUNDS
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2016, Vol 8, Issue 8
Abstract
Endophytic fungi that live asymptomatically inside the plant tissues have novel bioactive metabolites exhibiting a variety of biological activities, especially against cancer. This review highlights the research progress on the production of anticancer compounds by endophytic fungi from 1990-2015. Anticancer activity is generally associated with the cytotoxicity of the compounds present in the endophytic fungi. The ubiquitous nature of endophytic fungi synthesise diverse chemicals with promising anticancer activity from either their original host or related species. Modification in fermentation parameters and genetic insight of endophytes may produce novel anti-cancerous compounds.
Authors and Affiliations
Anand Dilip Firodiya, Rajesh Kumar Tenguria
Keywords
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