Endoscopic and Histopathologic Features in Patients of Portal Hypertensive Duodenopathy
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 4
Abstract
Objective: The aim of study is to describe the frequency of PHD in portal hypertension patients and its various clinical, endoscopic and histopathologic features. Methods: Ninety four patients with cirrhosis and portal hypertention were studied. Two duodenal biopsies from first and second part were obtained during upper endoscopy and sent for histopathologic examination. Twenty five dyspeptic patients were taken as control. Results: Endoscopic changes in duodenum during upper GI endoscopy were seen in 52 patients out of 94 patient (55.3%). These changes include erythema, erosion, ulcer and telangiectasia. Extending duodenal lesions were significantly higher in decompensated than in compensated cirrhotic patients. Erythema was the commonest lesion. ED (endoscopic duodenopathy) was significantly higher in patients of severe gastropathy (60.7%) than mild gastropathy (26.6%). Endoscopic Duodenopathy (ED) bleed was seen in 7.4%. ED was not related to variceal size and variceal bleed. Histopathologic changes includes capillary congestion, edema, apoptosis, fibrous changes and inflammation. These Histopathologic changes were not statistically significant between patients with or without ED. Conclusion: Portal hypertensive duodenopathy is not related to variceal size or variceal bleeding but it is significantly higher in patient having severe gastropathy. Portal hypertensive duodenopathy can be a cause of overt or obscure bleeding. Histopathologic duodenopathy is more prevalent than endoscopic duodenopathy.
Authors and Affiliations
Dr Mamta Sharma
Keywords
Related Articles
- EP ID EP511954
- DOI -
- Views 68
- Downloads 0
Giant Cutaneous Horn of Leg: A Case Report
A 35-year-old male presented with a giant cutaneous horn over the right leg. The patient was continuously exposed to minor trauma/ irritation at the site of development of the horn. There was bleeding from the base of ho...
Rare Presentation of Small Cell Neuroendocrine Carcinoma of Urinary Bladder
Small cell type neuroendocrine carcinoma of the bladder is a rare and aggressive tumour associated with poor prognosis. It often presents at a late stage than urothelial carcinoma of the bladder and comprises less than 1...
The Role of Fibrin Glue for Splenic Salvage in Grade I and II Splenic Injuries in Albino Rats and Rabbits
Introduction: Spleen is one of the most commonly injured abdominal organ in blunt trauma. Iatrogenic splenic injury accounts for 20% of all splenectomy. A better understanding of importance of the spleen, its role in imm...
Spontaneous Tuberculous Enterocutaneous Fistula at Iliac Crest – A Rare Case
Enterocutaneous fistula is an abnormal communication between bowel and skin. Most cases of enterocutaneous fistula (ECF) are iatrogenic and develop following abdominal surgeries. Other common causes are inflammatory bowe...
Pleomorphic Lipoma of Conjunctiva- A Rare Case Report
We present a rare case of pleomorphic lipoma, a bilateral sub conjunctival mass. In 62 years male, clinical futures and biopsy consists with Pleomorphic lipoma. The lesions were excised for symptoms and cosmetic reasons....