Enhanced Diuretic Effect of a Formulated Herbal Suspension -CAP
Journal Title: Saudi Journal of Medical and Pharmaceutical Sciences - Year 2018, Vol 4, Issue 5
Abstract
Abstract: A polyherbal suspension was formulated from the extracts of roots of Cyperusrotundus (CRR) and leaves of Azadirachtaindica(AIL) and Bryophyllumpinnatum (BPL). The suspension had very good redispersibility and was very stable without agglomeration, caking or microbial growth. Study of diuretic activity was done on individual plant extract as well as formulation. There was a significant increase in the volume of urine and electrolytes Na+,K+, Cl- which was similar to the standard drug furosemide. The formulation had much better activity as compared to the individual drug extracts which may be due to the synergistic effect of the herbs used. There was no significant change in pH. The loss in electrolytes Na+,K+, Cl- may leadto a reduction in supersaturation of calcium in urine thereby preventing the formation of kidney stone. The PHF have good diuretic activity and can be used to reduce hypertension, kidney problems and urolithiasis. Keywords: Diuretic activity, Cyperusrotundus roots, Meliaazadirachta leaves, Bryophyllumpinnatum leaves,Polyherbal suspension.
Authors and Affiliations
Ameeta Argal, Nishi Saxena
Keywords
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