Epidemiological Analysis of Central Nervous System Teratomas in SEER Database
Journal Title: Journal of Ankara University Faculty of Medicine - Year 2020, Vol 73, Issue 2
Abstract
Objectives: Teratomas are nongernimmatomatous germ cell tumors of the central nervous system. The aim of this study was to investigate the epidemiological features of central nervous system teratomas. Materials and Methods: Central nervous system teratomas were separated according to decades and localization using the United States National Cancer Institute [Surveillance, Epidemiology, and End Results Program (SEER)] database and demographic data were statistically analyzed retrospectively. Results: Four hundred and twenty-two patients diagnosed with teratoma were found in the SEER database. It was determined that 69% (n=293) of the patients had benign and 31% (n=129) had a malignant histological character. 87.6% (n=113/129) of malignant teratomas were detected in the first two decades. 56.7% (n=166/293) of benign teratomas were found in the first 3 decades of life. Among the lobes of the brain, teratomas are most frequently located in the frontal lobe (9.7%). The rate of teratomas in the pineal region was found to be 16.4%. Conclusion: Teratomas are frequently seen in the first two decades and approximately two-thirds of all teratomas are benign. While teratomas tend to localize from the brain lobes to the frontal lobe, the most common extra-axial localization is the pineal gland.
Authors and Affiliations
Ercan Bal, Recep Öztürk, Burak Bahadır, Ömer Faruk Türkoğlu, Mahmut Nedim Aytekin
Keywords
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- EP ID EP684823
- DOI 10.4274/atfm.galenos.2020.02997
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