EPIDEMIOLOGICAL AND CLINICAL PROFILES OF MELIOIDOSIS IN TERTIARY CARE CENTRE IN NORTHERN SRI LANKA
Journal Title: INTERNATIONAL JOURNAL OF RESEARCH IN PATHOLOGY AND MICROBIOLOGY - Year 2019, Vol 3, Issue 3
Abstract
Melioidosis is sporadically reported from various parts of Sri Lanka. It is major recent endemic in Northern Sri Lanla. It is caused by Burkholderia pseudomallei, a Gram-negative, oxidase positive bacillus. The first case of melioidosis was reported in a European tea broker in 1927 in Sri Lanka. We present a case series of seven patients of culture or serologically proven melioidosis from Northern Sri Lanka, highlighting the different clinical manifestations of the disease .Melioidosis had a varied presentation involving multiple abscesses in the skin, liver, spleen, mediastinum and septic arthritis. It presented as either an acute fulminant septicaemia with a high mortality to a chronic localized infection. Most cases had predisposing risk factors such as diabetes and occupational risk.
Authors and Affiliations
J Pradeepan, S Pirasath, T Kumanan
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