Epidemiological study of multi drug resistant tuberculosis at tertiary care hospital

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Epidemiological study of multi drug resistant tuberculosis at tertiary care hospital

Journal Title: MedPulse -International Medical Journal - Year 2015, Vol 2, Issue 11

Abstract

Introduction: Multidrug-resistant tuberculosis (MDR-TB) has emerged as a significant global health concern. There are alarming reports of increasing drug resistance from various parts of the globe which potentially threaten to disrupt the gains achieved in tuberculosis (TB) control over the last decade. MDR-TB is essentially man-made phenomenon and arises due to inadequate treatment of drug-sensitive TB. Aims and Objectives: To study the Epidemiological factors associated with Multi Drug Resistant Tuberculosis at Tertiary Care Hospital. Methodology: This is a cross-sectional, hospital based study of the patients admitted to TB inpatient department of a tertiary health Centre during March 2013 to March 2014, one year period, All the patients who has taken treatment Under DOT Centre of the health Centre after being suspect of the MDR TB, their sputum samples were send for Culture and drug sensitivity to State laboratories; at there these patients were confirmed as MDR TB Patients. All these MDR patients were studied and interviewed for the necessary data collection. At our tertiary health Centre; 80 TB patients were confirmed as MDR Patients included into the study. Result: The most common age for MDR TB patients in our study observed to be of 51-60 (23.75%) ; followed by 31-40 (16.25); 41-50 (15.00%); 61-70 (13.75%); 21-30 (11.25%); 11-20 (8.75%); >70 (6.25%) <10 (5.00%). Proportions of Males 70.00% were more than Female 30.00%. Most common associated condition with The MDR –TB patients were; (61.25%) MDR patients were Low Socioeconomic Status followed by H/O Alcohol addictions H/O (40%) Smoking (35%) Category of TB treatment: Defaulter (33.75%); Treatment failure (27.5%); Relapse (23.75%); New–case (17.5%). Irregular treatment (16.25%) Immuno-compromised Status (15%). Malnourished (BMI<18) (10%). Conclusion: In our study the most common conditions associated with the MDR–TB were Low Socioeconomic Status followed by H/O Alcohol addictions H/O; Smoking; Category of TB treatment: Defaulter; Treatment failure; Relapse; New–case; Irregular treatment; Immuno-compromised Status; Malnourished (BMI<18) so all these conditions should noted for the prevention of drug resistance in future.

Authors and Affiliations

Dipak Onkar Patil, Sanjay Dattu Mahajan

Keywords

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EP ID EP195761
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