Epidermal Growth Factor Versus Conventional Wound Dressings In Treatment Of Diabetic Ulcers- A Comparative Study
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 3
Abstract
With the advent of various advances in medical technology in twenty first century, many techniques have been tried to heal chronic leg ulcers. Although there exists no ideal wound dressing in the management of chronic wounds especially diabetic ulcers, several methods of wound dressing is being used and still evaluated. Hence we conducted the following study to evaluate the efficacy of Epidermal Growth Factor over conventional dressings in the healing of diabetic ulcers. The study was a prospective case control comparative Study titled “Epidermal growth factor versus conventional wound dressings in treatment of diabetic ulcers- A comparative study” done in the department of General Surgery, K S Hegde Medical Academy, during the time period August 2014 to August 2016, on cases of diabetic ulcers who visited the OPD and IPD of K.S. Hegde Hospital, Mangalore. Study was conducted on 40 consenting patients who met the predefined criteria, divided into 2 groups of 20 patients with the Epidermal growth factor dressing and 20 patients with conventional dressing. The data was collected in a proforma and the details transferred to a master chart and the results were analyzed. Statistical Analysis was done using SPSS software version 23.0. In our study we used paired t test to check the level of statistical significance. A „p‟ value less than 0.05(p<0.05) is considered significant. In our study a total of 40cases, of which 20 with conventional dressings and 20 with EGF dressings were studied. There was no significant difference in the demographic factors or the duration and size of the ulcer between the two groups of study. In our study males predominated in the study population. Acute wounds of less than I month duration were mostly studied. There was increased rate of granulation tissue formation and the size of the ulcer decreased drastically with EGF therapy In our study we concluded that Epidermal Growth Factor definitely has an edge over the conventional dressings in the healing of diabetic ulcers in terms of granulation tissue formation, and healing of the ulcer especially in diabetic wounds of less than one month duration.
Authors and Affiliations
Dr. Vimal Ramachandran, Dr. B Ramdas Rai, Dr. B Preetham Rai
Keywords
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- EP ID EP595507
- DOI 10.9790/0853-1603050915
- Views 119
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