Epidural Infusion of Inj. Bupivacaine Hydrochloride 0.125% Vs. Bupivacaine Hydrochloride 0.125% With Fentanyl Citrate for Post-Operative Analgesia Following Abdominal Surgery.
Journal Title: GJRA-Global Journal For Research Analysis - Year 2015, Vol 4, Issue 4
Abstract
We compared the postoperative epidural analgesia provided by the continuous epidural infusion of Bupivacaine hydrochloride with that provided By a continuous infusion of bupivacaine hydrochloride plus fentanyl citrate.100 patients were randomly allocated in 2 groups of n=50 each to receive drugs .Group 1: inj. Bupivacaine hydrochloride 0.125% Group 2: inj. Bupivacaine hydrochloride 0.125% and inj. Fentanyl citrate 2mcg/ml. Vitals,Visual analogue score, Sedation score and any side effects were observed. Adding fentanyl citrate 2 mcg/ml to bupivacaine hydrochloride 0.125% significantly reduced pain and increased quality of analgesia.Observation of side effects reflects that o.125% bupivacaine hydrochloride in group 1 has significant propensity to cause nausea and vomiting.Addition of inj. Fentanyl citrate 2mcg/ml to inj. Bupivacaine hydrochloride 0.125%for continuous epidural infusion significantly improved quality of analgesia, provided uniform stable analgesia without an attendant increase in side effects.
Authors and Affiliations
Vipul a Patel, Bhumika m Revar
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