EPIGENETICS OF REPRODUCTION
Journal Title: Folia Pomeranae Universitatis Technologiae Stetinensis Agricultura Alimentaria Piscaria et Zootechnica - Year 2016, Vol 39, Issue 328
Abstract
Epigenetic research offers a significant opportunity to understand the role of environmental interactions on the genome and disease, while enabling modulation of these interactions in order to improve human health. Knowledge of both genetic and epigenetic changes is essential for identification of functional gametes and for fertility treatment. Future studies in both human and animal models may enable better understanding of the mechanisms underlying the relationship between altered DNA methylation in the sperm cell and infertility. It is currently unclear whether methylation defects found in the DNA of infertile sperm are primary or secondary defects. An understanding of what underlies DNA methylation disorders will be important for the development of successful fertility treatments. While epigenetic research will unquestionably expand our knowledge of general genetics, it is mainly valued for its innovative and comprehensive approach to molecular diagnostics and is directed towards clinical procedures.
Authors and Affiliations
Magdalena CZUBASZEK, Katarzyna ANDRASZEK, Dorota BANASZEWSKA
Keywords
Related Articles
- EP ID EP411750
- DOI -
- Views 54
- Downloads 0
ASSESSMENT OF SOLAR RADIATION IN THE REGION OF LAKE MIEDWIE FOR RECREATIONAL PURPOSES
The aim of the paper is the assessment of the amount and variability of sums of global solar radiation, diffuse radiation and direct radiation in the area of Lake Miedwie and the resulting conditions for recreation. For...
THE INFLUENCE OF IBA, IAA AND NAA ON ROOTING OF CELOSIA ARGENTEA VAR.CRISTATA (L.) KUNTZE IN VITRO CULTURE
The formation of adventitious roots is an essential step in vegetative propagation. Well-developed root system allows for easier and faster adaptation of plants to ex vitro conditions. The aim of this study was to determ...
INNER-CITY BROWNFIELDS – GENESIS, SPECIFICS OF CONTAMINATION, POSSIBILITY OF RENEWAL
A city’s post-industrial areas are a reservoir of attractive urban space which can both be reused for industrial purposes or managed in a different way. The economic transformation of the post-industrial era caused a hig...
BODY CONDITION OF MALE FARM MINK (Neovison vison) DURING A MATING SEASON
The study was aimed to evaluate the relationship between the body condition of males of farmed mink (Neovison vison) and their behaviour as well as mating performance. The observations involved 170 males of Pearl mink. B...
INTER- AND INTRA-BREED VARIATION IN EJACULATE CHARACTERISTICS AND IN THE MORPHOLOGY, DIMENSIONS AND SHAPE OF SPERMATOZOA OF BOARS USED FOR ARTIFICIAL INSEMINATION
The aim of this study was to evaluate inter-bred and intra-breed variation in ejaculates and the morphology, dimensions and shape of spermatozoa of boars used for artificial insemination. The results obtained from this s...