ER PR Positive Vulval Leiomyoma with Myxoid Change Mimicking Bartholin’s Cyst- A Rare Presentation
Journal Title: Journal of Clinical and Diagnostic Research - Year 2017, Vol 11, Issue 12
Abstract
Vulval leiomyomas are rare entities which are seen in the reproductive age group. They are most commonly misdiagnosed as Bartholin’s cyst or Bartholin’s abscess when presenting with features of inflammation. Excisional biopsy is the treatment of choice. Besides this, Estrogen Receptor (ER) and Progesterone Receptor (PR) positivity implicates the usefulness of adjuvant hormonal therapy. We present a case of 38-year-old female who presented with a vulval swelling. She was misdiagnosed clinically as Bartholin’s cyst. Marsupialization of the cyst was done and tissue was sent for histopathology. Microscopy confirmed the diagnosis of vulval leiomyoma with myxoid changes. Additionally, immunohistochemical stains were was also applied, which showed positivity for Vimentin, Desmin, ER and PR and negativity for Pan Cytokeratin (CK), S100. ER and PR positivity is a rare finding in case of leiomyoma with myxoid changes.
Authors and Affiliations
MITHILA BISHT, RANJAN AGRAWAL, MENKA VERMA, PARBODH KUMAR
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