ER PR Positive Vulval Leiomyoma with Myxoid Change Mimicking Bartholin’s Cyst- A Rare Presentation
Journal Title: Journal of Clinical and Diagnostic Research - Year 2017, Vol 11, Issue 12
Abstract
Vulval leiomyomas are rare entities which are seen in the reproductive age group. They are most commonly misdiagnosed as Bartholin’s cyst or Bartholin’s abscess when presenting with features of inflammation. Excisional biopsy is the treatment of choice. Besides this, Estrogen Receptor (ER) and Progesterone Receptor (PR) positivity implicates the usefulness of adjuvant hormonal therapy. We present a case of 38-year-old female who presented with a vulval swelling. She was misdiagnosed clinically as Bartholin’s cyst. Marsupialization of the cyst was done and tissue was sent for histopathology. Microscopy confirmed the diagnosis of vulval leiomyoma with myxoid changes. Additionally, immunohistochemical stains were was also applied, which showed positivity for Vimentin, Desmin, ER and PR and negativity for Pan Cytokeratin (CK), S100. ER and PR positivity is a rare finding in case of leiomyoma with myxoid changes.
Authors and Affiliations
MITHILA BISHT, RANJAN AGRAWAL, MENKA VERMA, PARBODH KUMAR
Keywords
Related Articles
- EP ID EP367571
- DOI 10.7860/JCDR/2017/30626.10997
- Views 59
- Downloads 0
Molecular Investigation of a Suspected Myeloproliferative Neoplasm in Patients with Basophilia
Letter to Editor
Imaging in a Case of Extensive Paediatric Mediastinal Lymphoma Presenting as Haemothorax
ABSTRACT Lymphomas are the third most common paediatric malignancies and the most common paediatric mediastinal masses. On imaging they present as large, lobulated, homogenous, predominantly anterior mediastinal masses w...
Correspondence: Correlation of Salivary pH, Incidence of Dental Caries and Periodontal Status in Diabetes Mellitus Patients: A Cross-Sectional Study
Letter to Editor
Assessment of Insulin Sensitivity and its Convalescence with Dietary Rehabilitation in Undernourished Rural West Bengal Population
Introduction: Metabolic syndrome involving diabetes is acquiring the eminence of prospective epidemic in India with dramatic rise in rural population prevalence where majority are undernourished and creates significant h...
Standardisation and Evaluation of Direct MTT Rifampicin Tube Assay for Sputum against Smear Grading, Volume and Turnaround Time
ABSTRACT Introduction: WHO has rolled out rapid molecular methods for detection of rifampicin resistance. However, the same are not yet accessible at all the laboratories which are still dependent on alternative methods....