Erythrocytes and Platelets: A Critical Analysis of their Ontogenic Relationship through Automated Parameters
Journal Title: Journal of Clinical and Diagnostic Research - Year 2017, Vol 11, Issue 5
Abstract
Introduction: Erythrocytes and platelets share an intimate development history, due to which special interest is centered on their relationship. Mature Red Blood Cells (RBCs) and platelets show a similar physiological rhythm, and are concurrently involved in numerous pathologic states. Aim: To identify subtle relationships between various RBC and platelet parameters with an objective to analyse if a linear correlation co-exists between and among them in physiological/ pathological states. Materials and Methods: A prospective analysis of 1250 EDTA blood samples was conducted. The five RBC parameters (RBC count, HCT, MCV, RDW, Hb) and four platelet parameters (platelet count, PCT, MPV, PDW) obtained from each case were statistically analysed for linear dependence. Results: A statistically significant direct linear relationship was found between RDW with platelet count and PCT. A statistically significant inverse linear relationship was noticed between the following parameters: i) HCT with platelet count and PCT; ii) MCV with platelet count and PCT; iii) Haemoglobin and platelet count. Conclusion: A linear correlation, either direct or inverse, was seen among various parallel RBC and platelet parameters.
Authors and Affiliations
Deepak Kumar, PadmaPriya Kasukurti, Srinivasa Murthy
Rare Isolate of Stephanoascus ciferrii from the Aural Discharge of Post-mastoidectomy Patient-A Case Report
ABSTRACT Stephanoascus ciferrii is an ascomycetous yeast-like fungus, rarely causing human infections. It is also a teleomorph of Candida ciferrii. This species has a strong tendency to become resistant especially in pat...
Twain Impaction-A Novel Orthodontic Approach
ABSTRACT Primary failure of eruption (PFE) contend one of the varied rationale for etiology of malocclusions with eruption sequence disturbances. In a contemporary world of modernisation and advanced technological innova...
Seroprevalence of Mycoplasma pneumoniae and Clinical Profile of Affected Patients in a Tertiary Care Hospital
ABSTRACT Introduction: Mycoplasma pneumoniae is the most common causative agent of community acquired pneumonia. Rapid and reliable method for the diagnosis of Mycoplasma pneumoniae infection is important for the appropr...
Is Low Cholesterol a Predisposing Factor for Primary Intracerebral Haemorrhage? A South Indian Perspective
ABSTRACT Introduction: Stroke is an important cause of mortality and morbidity in low-income and middle-income countries like India. Primary Intracerebral Haemorrhage (PICH) refers to Intracerebral Haemorrhage (ICH) in t...
Palmer Freckling as a New Clinical Marker: Clinico-epidemiological Study of 26 Cases of Neurofibromatosis Type-1
ABSTRACT Introduction: Neurofibromatosis Type 1 (NF-1) is an autosomal dominant genodermatosis characterised by Café Au lait Macules (CALMs), multiple neurofibromas, iris Lisch nodules, axillary and inguinal freckling an...