Esophageal and Gastric T-Cell Lymphoma: A Rare Entity
Journal Title: Journal of Krishna Institute of Medical Sciences University - Year 2012, Vol 1, Issue 1
Abstract
Background: Primary gastrointestinal T-cell lymphomas are extremely rare entity and are much less common than B-Cell lymphomas. Case History: A primary T-cell lymphoma was diagnosed in an octogenarian African American male with a history of diabetes mellitus type-II, remote history of prostate cancer, hypertension, obesity and hyperlipidemia. He had symptoms of dysphagia, early satiety, loss of appetite and loss of weight. He was Helicobacter pylori IgG antibody positive and on treatment. Result of first biopsy during endoscopy showed only heavy lymphoid infiltrate. But, due to high suspicion of malignancy, a second upper gastrointestinal endoscopy and biopsy was performed .This biopsy from the large deep 3cm friable ulcer with nodular base from esophagus was taken which showed atypical lymphoid cells positive for CD3 and CD7 and negative for CD5, CD4, CD8 and CD56. The combination of the histological, immunohistological stain results and the gene rearrangement results confirmed T cell lymphoma. The patient died after 5 months after 5 cycles of chemotherapeutic agents of severe dehydration and complications from sepsis.
Authors and Affiliations
Raja Shekhar R. Sappati Biyyani, Manoj Kumar Bupathi, Amy Soloman, Annette Kyprianou
Keywords
Related Articles
- EP ID EP103103
- DOI -
- Views 103
- Downloads 0
Primary Psoas Abscess in an Immunocompromised Patient Caused by Streptococcus intermedius and Escherichia coli
Psoas abscess is a rare medical disease. Streptococcus intermedius is a commensal of the mouth and the upper respiratory tract but can cause various pyogenic infections especially liver and brain abscesses but rarely mus...
Paget-Schroetter Syndrome in 52-Year-Old Male: An Interesting Case Report
Paget-Schroetter syndrome is a form of upper limb deep venous thrombosis and it is commonly seen in young individuals. Paget-Schroetter syndrome is a rare condition and diagnosis becomes more difficult if it occurs in ol...
First 1000 Days Fixed Deposit –Towards Healthy Life
Rat Cerebellar Microanatomy and Neural Oxidative Redox Differentially Affected by Black Mustard Seeds Extract
Background: Structural and functional alterations in cortical anatomy by environmental stressors are associated with several neuropsychiatric disorders. Many of these changes are supposed to fore start disease onset and...
Epidemiological, Clinico-Pathological Profile and Management of Colorectal Carcinoma in a Tertiary Referral Center of Eastern India
Background: The colorectal carcinoma is a common cancer in males and in females and second most common cause of death in Europe and third commonest cause in the United States. Recent Indian study shows that there is a si...