Esophageal and Gastric T-Cell Lymphoma: A Rare Entity

Journal Title: Journal of Krishna Institute of Medical Sciences University - Year 2012, Vol 1, Issue 1

Abstract

Background: Primary gastrointestinal T-cell lymphomas are extremely rare entity and are much less common than B-Cell lymphomas. Case History: A primary T-cell lymphoma was diagnosed in an octogenarian African American male with a history of diabetes mellitus type-II, remote history of prostate cancer, hypertension, obesity and hyperlipidemia. He had symptoms of dysphagia, early satiety, loss of appetite and loss of weight. He was Helicobacter pylori IgG antibody positive and on treatment. Result of first biopsy during endoscopy showed only heavy lymphoid infiltrate. But, due to high suspicion of malignancy, a second upper gastrointestinal endoscopy and biopsy was performed .This biopsy from the large deep 3cm friable ulcer with nodular base from esophagus was taken which showed atypical lymphoid cells positive for CD3 and CD7 and negative for CD5, CD4, CD8 and CD56. The combination of the histological, immunohistological stain results and the gene rearrangement results confirmed T cell lymphoma. The patient died after 5 months after 5 cycles of chemotherapeutic agents of severe dehydration and complications from sepsis.

Authors and Affiliations

Raja Shekhar R. Sappati Biyyani, Manoj Kumar Bupathi, Amy Soloman, Annette Kyprianou

Keywords

Related Articles

Assessment of Iron Overload in Homozygous and Heterozygous Beta Thalassemic Children below 5 Years of Age  

Background:[/i] Thalassemia is a genetic disease having 3-7% carrier rate in Indians. It is transfusion dependent anemia having high risk of iron overloading. A clinical symptom of iron overload becomes detectable in...

 Moya Moya Disease: Presenting With Changing Neurological Signs

A 4 yrs old female child was admitted with left hemiparesisand unconsciousness and a short history ofneurological impairment, changing neurological signswith progress of the disease and most of relevant laboratoryinvesti...

Primary Non-Hodgkin’s Lymphoma of Thyroid Gland – Report of a Rare Case 

Goiter is a common presentation of neck swelling seen in surgical outpatient department. 20% of Goiter cases present with some form of malignancy. Primary lymphoma is relatively uncommon malignancy of the thyroid, co...

Infiltrating Ductal Carcinoma Arising in Fibroadenoma and Associated Proliferative Mammary Disease in a 38 Years Old Female -A Rare Case Report

Infiltrating ductal carcinoma arising in a fibroadenoma is a rare incidental finding. Incidence is 0.002-0.0125%. Women having proliferative disease without atypia have a twofold elevation in their risk for subsequent in...

Effect of Body Mass Index on Postural Balance and Muscle Strength in Children Aged 8-10 years

Background: Childhood overweight and obesity, which are considered as global epidemic, can be assessed using Body Mass Index (BMI). BMI difference can lead to anatomic changes due to an increased body load. This increase...

Download PDF file
  • EP ID EP103103
  • DOI -
  • Views 102
  • Downloads 0

How To Cite

Raja Shekhar R. Sappati Biyyani, Manoj Kumar Bupathi, Amy Soloman, Annette Kyprianou (2012). Esophageal and Gastric T-Cell Lymphoma: A Rare Entity. Journal of Krishna Institute of Medical Sciences University, 1(1), 122-126. https://europub.co.uk/articles/-A-103103