Establishment of blending control for Hand operated Double Cone Blender
Journal Title: International Journal of Drug Regulatory Affairs - Year 2018, Vol 6, Issue 2
Abstract
In the current study, a fundamental approach is used to establish operation procedure, for a hand operated double cone blender. Initially, assuming for a potent drug, where in, the strength of the drug is very less in the final dosage form, a one percent concentration of potassium permanganate with respect to final one kilogram of blended powder using starch as diluent was planned. With a kind of geometric progression method, at a rate of 10 rotations per minute, the final outcome of the uniform distribution of the potassium permanganate was found to be for at least for fourteen hours of rotations, leading to concentration range of potassium permanganate 0.08 ± 0.025 mg per mg of final blended powder
Authors and Affiliations
Subba Rao Bayya, Anuroop Raveendran, Ratnakar Baki, Adithya Jinuka
Keywords
Related Articles
- EP ID EP329308
- DOI 10.22270/ijdra.v6i2.233
- Views 83
- Downloads 0
Informed Consent form in Clinical Trial
Informed consent form is a vital requirement for research study on the human participant. It is the consent which is given by the subject before participate in clinical trial. Informed consent mainly came in existence af...
FORMULATION AND IN-VITRO EVALUATION OF HOLLOW MICROSPHERES OF GLIPIZIDE
Present work involves attempts to improve floating time of glipizide by formulation of hollow microspheres incorporating Glyceryl Monostearate and acryflow. The floating microspheres were evaluated for percentage yield,...
REGULATIONS OF ORPHAN DRUGS IN USA, EU AND INDIA-A COMPARATIVE STUDY
Orphan drugs are the drugs and natural products used in treatment, diagnosis, or prevention of rare disease. The orphan drug regulation varies in different countries. Initially a guideline (Orphan Drug Act) for orphan dr...
Regulatory requirements for Vaccine registration in United States
Vaccination is one among the foremost cost-efficient health interventions out available, saving a lot of individuals from illness, incapacity, and death annually. No alternative countermeasures are effective in reducing...
Regulation of Blood and Blood products in India, USA and EU
Blood and blood products are precious commodity which gives life to another person. Though we have immense discoveries and invention in science and technology, yet we cannot make blood hence, human blood has no substitut...