Estimation of anti-inflammatory, analgesic, thrombolytic activities of Sonneratia caseolaris linn. (Family: sonneratiaceae)
Journal Title: International Journal of Unani and Integrative Medicine - Year 2018, Vol 2, Issue 3
Abstract
In this study, Sonneratia caseolaris was evaluated for its anti-inflammatory, analgesic and thrombolytic activities using different systems assay. The anti-inflammatory activity, the % of inhibition of paw edema of crude methanol extract showed the highest activity in leaf (58.24% inhibition) at 100 µg/ml, in bark (40.80% inhibition) at 200 µg/ml. The analgesic activity, the effect of each extractive at two different concentration (100 & 200 µg/ml) on the response of mice was measured. The most potent activity was also found in crude methanolic fraction (CME) showed in leaf highest % of inhibition (25.93 at 100 µg/ml) and in bark highest % of inhibition (33.33 at 100 µg/ml) after standard (Diclofenac-Na). Hence, it is worthwhile to isolate and elucidate the bioactive principles that are responsible for the better activity that is underway.
Authors and Affiliations
Md. Shariful Islam, Md. Atikur Rahman Ope, Mohshin Kabir, Sabiha Ferdowsy Koly, Md. Morad Biswas, Shaikat Hossain, Md. Sharif Ahammed, Sadia Afrin
Keywords
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