Estimation of GCF Alkaline Phosphatase Levels in Health and Periodontal Disease – A Clinico Biochemical Study
Journal Title: International Journal of Contemporary Medical Research - Year 2018, Vol 5, Issue 7
Abstract
Introduction: Periodontitis is an inflammatory disease that is a common cause for damage to gingiva and periodontal tissue and for the loss of teeth. Tooth mobility, pathological migration and alveolar bone loss are common sequelae of periodontitis. Two types of periodontitis known are Chronic and Aggressive type. In gingival crevicular fluid (GCF), the activity of Alkaline phosphatase has been considered as a useful diagnostic and prognostic marker of periodontal disease. Based on this observation, a study has been conducted in patients with chronic and aggressive periodontitis and their age and gender matched healthy controls to assess the ALP levels in GCF. Material and methods: GCF alkaline phosphatase activity was observed in patients with aggressive and chronic periodontitis and their age and gender matched healthy controls. Results: On Comparison between GCF alkaline phosphatase levels between both aggressive and chronic periodontitis and their age and gender matched controls, the mean difference was statistically significant (P < 0.01) when paired t test was used. Conclusion: In patients with aggressive and chronic periodontitis, the mean alkaline phosphatase levels were increased significantly in comparison to healthy controls.
Authors and Affiliations
Durga Bai Yendluri, Aditi R
Keywords
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