Estrogen Receptor α and β Status in Hypertensive Postmenopausal Women with Co-morbidities
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 1
Abstract
Menopause is accompanied by decline in estrogen levels and a substantial rise in the incidence of hypertension in majority of women. Whether this decline is in accordance with estrogen receptor levels and associated comorbidities need to be elucidated. Hence estrogen receptor status was assessed among selected hypertensive postmenopausal women with co-morbidities. A total of 12 postmenopausal women were selected and categorised into normotensive postmenopausal women (group-1), hypertensive postmenopausal women (group-2) hypertensive postmenopausal women with diabetes (group-3) and hypertensive postmenopausal women with renal insufficiency (group-4). Levels of estrogen receptor α and estrogen receptor β were assessed in these groups of postmenopausal women. One way ANOVA was performed using SPSS16.0 statistical software. No significant difference was found in estrogen receptor α levels between the groups. However, estrogen receptor β levels were significantly elevated in hypertensive postmenopausal women with renal insufficiency (group-4). The expression of these receptors might depend on the availability of estradiol. ERβ levels were found to increase with co-morbid conditions
Authors and Affiliations
Salini A
Keywords
Related Articles
- EP ID EP210482
- DOI -
- Views 100
- Downloads 0
Prevalence and Antibiogram of Vaginal Carriage of Group B Streptococci in Third Trimester of Pregnancy and Its Feto-Maternal Outcome
Background and Objectives: Group-B Streptococcal (GBS) prevalence varies from place to place and this organism is responsible for serious infections in newborns such as septicemia and meningitis. This study was undertake...
Clinico-Heamatological Study of Dengue in Adults and the Significance of Total Leukocyte Count in Management of Dengue
Background: Dengue is the most rapidly spreading mosquito borne viral disease in the world. There is an increase in incidence of dengue in adult population in South Asian countries in recent years. Objective: To study th...
Utility of Red Flag Symptoms in Prediction of Malignancy in Elderly Patients with Dyspepsia
Introduction: The elderly vulnerable population is increasing world-wide. Dyspeptic symptoms are common in the general population; with frequencies ranging from 10% to 45%. Red flags or alarm symptoms can be useful to pr...
Evaluation of Breast Masses in Hilly Areas, an Initial Experience
Objective: Evaluation of breast masses with mammography and sonography and comparison with Fine Needle Aspiration Cytology (FNAC)/ histopathology examination. Materials and Method: The study consisted of 25 women with in...
Studies on Attituide of Staff Nurses Regarding Their Legal Responsibilities in Selected Hospitals of J&K State
To find out the attitude of staff nurses regarding their legal responsibilities in some selected hospitals of Jammu and Kashmir State, sixty numbers of subjects (nurses) were questioned by simple random sampling techniqu...