Estrogen Receptor α and β Status in Hypertensive Postmenopausal Women with Co-morbidities

Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 1

Abstract

Menopause is accompanied by decline in estrogen levels and a substantial rise in the incidence of hypertension in majority of women. Whether this decline is in accordance with estrogen receptor levels and associated comorbidities need to be elucidated. Hence estrogen receptor status was assessed among selected hypertensive postmenopausal women with co-morbidities. A total of 12 postmenopausal women were selected and categorised into normotensive postmenopausal women (group-1), hypertensive postmenopausal women (group-2) hypertensive postmenopausal women with diabetes (group-3) and hypertensive postmenopausal women with renal insufficiency (group-4). Levels of estrogen receptor α and estrogen receptor β were assessed in these groups of postmenopausal women. One way ANOVA was performed using SPSS16.0 statistical software. No significant difference was found in estrogen receptor α levels between the groups. However, estrogen receptor β levels were significantly elevated in hypertensive postmenopausal women with renal insufficiency (group-4). The expression of these receptors might depend on the availability of estradiol. ERβ levels were found to increase with co-morbid conditions

Authors and Affiliations

Salini A

Keywords

Related Articles

Role of B Mode in Evaluating Malignant Breast Masses

Background: Breast cancer now represents the most common female malignancy in developing and developed world, and is the second leading cause of cancer death among women. USG is an ideal imaging modality due to its cost...

Visual Evoked Responses (VERS) in Assessment of Optic Nerve Injury in Head Injury Patients

As we are getting more industrialised and travelling is becoming more frequent, incidence of fatal road side accident resulting in head injury is also increasing. It is difficult to assess the visual status/ state of opt...

How to Minimize Corneal Astigmatism during Cataract Surgery

Aims: To study the corneal astigmatism in manual small incision cataract surgery following temporal incision, superior incision, superotemporal incision and superior incision with infinity suture. Setting: Government Med...

Role of Multiparametric MRI Prostate as A Screening Tool for Cancer Detection

Diagnostic screening for prostate cancer includes digital rectal examination and serum PSA. However several studies have shown that screening using serum PSA and digital rectal examination, did not significantly decrease...

Factors Determining Outcome in Multivisceral Resection for Gastric Cancer – A South Indian Tertiary Care Centre Observational Study

Gastric cancer is one of the leading cause of cancer related deaths. In India, Chennai, has a very high incidence of 11.8/100000 among males and 5.9/100000 among females. The resectability rate for gastric cancer is abou...

Download PDF file
  • EP ID EP210482
  • DOI -
  • Views 97
  • Downloads 0

How To Cite

Salini A (2015). Estrogen Receptor α and β Status in Hypertensive Postmenopausal Women with Co-morbidities. Journal of Medical Science And clinical Research, 3(1), 3789-3798. https://europub.co.uk/articles/-A-210482