Ethical and Social Issues in Fertility Preservation
Journal Title: Chettinad Health City Medical Journal - Year 2018, Vol 7, Issue 3
Abstract
Fertility preservation is the cryopreservation of gametes (spermatozoa, oocytes), embryos, testicular tissue, and ovarian tissue in order to have a choice of reproduction in the future. This is crucial in patients affected with cancer or other severe medical diseases whose treatment hampers the fertility potential of an individual. Fertility preser- vation however, raises a lot of ethical issues in each group of patients. The general limitations that apply to cryopreservation are the quality of the biological material cryopreserved, post-thaw survival rate, and the efficacy & safety of experimental protocols (gonadal tissue and whole ovary cryopreservation). Additionally, there are ethical concerns that impact fertility preservation, like obtaining informed consent from pre-pubertal adolescents with cancer, delaying treatment in cancer patients for the sake of fertility and possible reintroduction of malignancy post auto-transplantation of the frozen-thawed reproduc- tive tissue. Fertility preservation by cryopreservation of gametes and embryos offers hope to many, while gonadal tissue cryopreservation is still in its infancy and therefore long term follow-up studies are required to monitor the safety of the techniques and the health of children born out of such procedures.
Authors and Affiliations
prathima tholeti, Ranjani S, Pandiyan N
Keywords
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