Ethnopharmacological Knowledge for Management of Oral Mucositis in Zahedan, Southeast Iran

Journal Title: Turkish Journal of Pharmaceutical Sciences - Year 2021, Vol 18, Issue 2

Abstract

Objectives: Oral mucositis is among the complications of cancer therapy that affects quality of life and imposes remarkable financial costs for patients with cancer. This study aimed to explore, preserve, and scientifically investigate the ethnomedicinal knowledge of traditional healers for treatment of oral mucositis in Zahedan, Iran. Materials and Methods: Field surveys were performed from September 2018 to October 2018 in Zahedan. Data was collected using a structured questionnaire in Persian. All species recorded for the treatment of oral mucositis were sampled. Samples were identified by a botanist and a voucher specimen of them was deposited in the Herbarium Center of the Faculty of Pharmacy in Kerman, Iran. Information, such as scientific name, family, local name, parts used, and preparation method, were also provided. Literature review on available data on effect of the addressed plant species on mucositis and other relative pharmacological actions, such as wound healing and anti-inflammatory properties, was performed. Results: A total of 29 informants (attars) were interviewed and 18 medicaments were recommended, of which three samples were of synthesis or mineral origin and 15 samples were of herbal origin. Drugs were administered both topically and orally. According to recent studies, two herbs were evaluated for their direct effect on mucositis. Some pharmacological properties related to mucositis treatment by the other 11 samples have been confirmed. Conclusion: This study provides information on the characteristics of medicinal plants from Zahedan, Iran based on their ethnopharmacological knowledge and pharmacological properties for mucositis treatment.

Authors and Affiliations

Fatemeh Sadat HASHEMINASAB, Fariba SHARIFIFAR, Seyed-Mehdi HASHEMI, Mohammad SETAYESH

Keywords

Related Articles

Spectrophotometric Determination of Dopamine in Bulk and Dosage Forms Using 2,4-Dinitrophenylhydrazine

Objectives: Dopamine (DA) hydrochloride is a sympathomimetic agent used therapeutically for the correction of hemodynamic disorders associated with shock episodes. Although several analytical methods have been described,...

Flavonoids Isolated from Vitex grandifolia, an Underutilized Vegetable, Exert Monoamine A & B Inhibitory and Anti-inflammatory Effects and Their Structure-activity Relationship

Objectives: Vitex grandifolia belongs to family Lamiaceae; it consists of flowering plants and it is also called the mint family. The Yoruba people of southwest Nigeria called it “Oriri” or “Efo oriri”. This plant is cla...

Determining the Best Poloxamer Carrier for Thiocolchicoside Solid Dispersions

Objectives: The aim of this study of this study was to discover the best poloxamer as a solid dispersion carrier for thiocolchicoside (TCS). Materials and Methods: The compatibility of TCS with excipients was studied by...

Effects of Glycyrrhetic Acid on Human Chronic Myelogenous Leukemia Cells

Objectives: Chronic myelogenous leukemia (CML) is a type of blood cancer that is initially treated with imatinib (first Abl kinase inhibitor). However, some patients with CML develop imatinib resistance. Several new gene...

Download PDF file
  • EP ID EP694448
  • DOI 10.4274/tjps.galenos.2020.67355
  • Views 102
  • Downloads 0

How To Cite

Fatemeh Sadat HASHEMINASAB, Fariba SHARIFIFAR, Seyed-Mehdi HASHEMI, Mohammad SETAYESH (2021). Ethnopharmacological Knowledge for Management of Oral Mucositis in Zahedan, Southeast Iran. Turkish Journal of Pharmaceutical Sciences, 18(2), -. https://europub.co.uk/articles/-A-694448