ETHOSOMAL DRUG DELIVERY SYSTEM: A REVIEW
Journal Title: Indo American Journal of Pharmaceutical Research - Year 2012, Vol 2, Issue 4
Abstract
The vesicles have been well known for their important in cellular communication and particle transportation for many years. Researchers have understood the properties of vesicle structures for use in better drug delivery within their cavities, that would allow to tag the vesicle for cell specificity. Vesicles would also allow to control the release rate of drug over an extended time, keeping the drug shielded from immune response or other removal systems and would be able to release just the right amount of drug and keep that concentration constant for longer periods of time. One of the major advances in vesicle research was the finding a vesicle derivative, known as an ethosomes. Ethosomes are modified lipid carriers that enable drugs to reach into deeper skin layers and/or systemic circulation, and represent a lipid vesicular carrier system embodying ethanol in relatively high concentration and are very effective in delivering drugs into and across the skin.
Authors and Affiliations
N. B. MAHALE, S. A. KHAIRNAR, R. N. KANAWADE, K. K. WALE, D. D. NAVANDAR, S. R. CHAUDHARI
Keywords
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