ETHOSOMAL DRUG DELIVERY SYSTEM: A REVIEW
Journal Title: Indo American Journal of Pharmaceutical Research - Year 2012, Vol 2, Issue 4
Abstract
The vesicles have been well known for their important in cellular communication and particle transportation for many years. Researchers have understood the properties of vesicle structures for use in better drug delivery within their cavities, that would allow to tag the vesicle for cell specificity. Vesicles would also allow to control the release rate of drug over an extended time, keeping the drug shielded from immune response or other removal systems and would be able to release just the right amount of drug and keep that concentration constant for longer periods of time. One of the major advances in vesicle research was the finding a vesicle derivative, known as an ethosomes. Ethosomes are modified lipid carriers that enable drugs to reach into deeper skin layers and/or systemic circulation, and represent a lipid vesicular carrier system embodying ethanol in relatively high concentration and are very effective in delivering drugs into and across the skin.
Authors and Affiliations
N. B. MAHALE, S. A. KHAIRNAR, R. N. KANAWADE, K. K. WALE, D. D. NAVANDAR, S. R. CHAUDHARI
Keywords
Related Articles
- EP ID EP222195
- DOI -
- Views 115
- Downloads 0
KINETICS AND MECHANISM OF OXIDATION OF AZO DYE ACID YELLOW 36 BY CHLORAMINE-T IN HYDROCHLORIC ACID MEDIUM
Abstract Kinetics of oxidative decolorization of Acid yellow36 (AY36) by chloromine-T,(CAT) in hydrochloric acid (HCl) medium at 301 K has been investigated spectrophotometrically at λmax439nm. The reaction showed first...
NEEDLELESS INJECTION SYSTEM: AN OVERVIEW
Abstract Needle-less injections are designed to solve the problem associated with hypodermic needle injection. Needle-less injection system was first introduced by Marshell Lockhart in1936. Needle-less system is based on...
CONTROLLED RELEASE PELLETS: AN EFFECTIVE TOOL IN CHRONIC THERAPY
Abstract Multiparticulate drug delivery systems like pellets, granules, micro particles, minitablets etc., prove to be promising and highly flexible systems with ease of formulating with different drug release kinetics....
THE TRADITIONAL USES AND PHARMACOLOGICAL ACTIVITIES OF MUCUNA PRURIENS (L)DC: A COMPREHENSIVE REVIEW
Abstract Medicinal plants have served as a constant source of medicaments, which have a great efficacy and demand for the treatment of various diseases. One of the plants, that deserve attention is Mucuna pruriens. The p...
EVALUATION OF ACTIVE COMPOUNDS OF FENUGREEK SEEDS OF WATER EXTRACT USING HPLC METHODOLOGY
Abstract Methi seeds and its uses in Ayurvedic medicines for the treatment of wounds, abscesses, arthritis, bronchitis, and digestive disorders have been reported due to presence of bioactive compounds. These active comp...