Etkin Antitüberküloz Tedaviden Üç Yıl Sonra Ortaya Çıkan İntrameduller Spinal Tüberküloma: Olgu Sunumu
Journal Title: Journal of Neurological Sciences-Turkish - Year 2006, Vol 23, Issue 2
Abstract
Santral sinir sistemi tüberkülozu menenjit, tuberkuloma ya da spinal tüberküloz olarak ortaya çıkabilir. Tuberkulomaların antitüberküloz tedavi altında paradox olarak ortaya çıkması literatürde sık olarak bildirilmesine rağmen, tam ve düzgün tedavi almış olgularda, geç dönemde ortaya çıkmaları oldukça nadir bildirilmiştir. Bu çalışmada antitüberküloz tedavi altında intrakranial ve spinal tüberküloma gelişen, 18 aylık tedavi sonrası klinik ve radyolojik tam düzelme gösteren ancak tedavi bitiminden üç yıl sonra spinal tüberkuloma ortaya çıkan 28 yaşında bir erkek olgu sunulmuştur. Bu olgu SSS tüberkülozu tanısı almış olan olguların düzgün tedavi almış olsalar bile uzun süreli takibinin gerekliliğini vurgulamaktadır. Halen kullanılmakta olan klasik antitüberküloz ilaçlar metabolik olarak aktif mikobakteriler üzerine etkin olduklarından ve latent organizmalara karşı etkisiz kalabildiklerinden, Mikobakterium Tuberkülozis tedavisinde latent organizmaları da etkileyebilecek yeni tedavi stratejilerine ihtiyaç vardır.
Authors and Affiliations
Aysun UNAL, Nevin SUTLAS, Demet KUSCU, Dursun KIRBAS
Keywords
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