Evaluating the Effectiveness of Peptic Ulcer Disease Therapy in Adolescents from the Perspective of Quality of Life Criteria
Journal Title: Здоров`я дитини - Year 2016, Vol 5, Issue 73
Abstract
The article presents the results of the study on the quality of life in children aged 14–17 years, suffering from a stomach ulcer and/or duodenal ulcers. Introduction. When assessing the effectiveness of different treatments, it has been proved that clinical parameters are not enough for the complete verification of response to therapy. The quality of life indexes should be included to the list of criteria for evaluating the effectiveness of treatment. Objective: to assess the effectiveness of drug treatment for peptic ulcer disease in adolescents aged 14 to 17 years with the help of international questionnaire PedsQL™ 4.0 and to determine the feasibility of its use in pediatric practice. Materials and methods. The study involved 50 children with the diagnosis «stomach ulcer and/or duodenal ulcer, acute stage» aged 14–17 years. Evaluation of the quality of life of patients was carried out on admission to hospital and 1 month after treatment wit the help of PedsQL™ 4.0 questionnaire using separate forms for children and parent. Results. When comparing the quality of life at baseline and after a month, we can conclude that the parameters of physical, emotional, psychosocial and school functioning became significantly higher during the survey of both children and their parents. When filling out the questionnaire by children, their quality of life indices were significantly higher than when filling the questionnaire by their parents, on the scales of physical functioning, school life, psychosocial functioning and the mean value of all scales. This difference was found before and during the treatment, and one month after received therapy. Conclusion. The significant increase in most indicators on the PedsQL™ 4.0 questionnaire 1 month after received treatment, according to approved protocols, demonstrates the possibility of using this tool for assessing the quality of life as an additional criterion for efficacy of drug therapy of peptic ulcer in adolescents.
Authors and Affiliations
S. L. Nyankovsky, O. R. Sadova
The Role of Physical Activity in Everyday Life of Contemporary Students Studied by Various Programs
Background. The question of physical activity becomes more urgent every day. More and more parents think about the necessity of physical development of children at the same level as mental. So the studying of physical ac...
Pompe disease clinical and laboratory diagnostic features
Background. Analysis of Pompe disease (PD) clinical features in children in order to determine its main clinical and laboratory characteristics based on the results of laboratory and instrumental studies that allow to se...
Bacterial Lysates as a Key Drug Component of the Prevention and Treatment for Acute Respiratory Infections in Children
The article describes the possibilities of the control of innate and adaptive immunity by medications, in particular through the use of bacterial lysate Broncho-munal®. Immunoregulatory role of bacterial lysates is prese...
Modern Problems of Andrology in Children
Introduction. Recently, the number of infertile men significantly increased, the factors of this condition are largely related to childhood and adolescence. Objective. To predict the role of surgical interventions in chi...
«Guess the Melody», or Multicomponent Cyclic and Noncyclic Infectious Processes in the Pediatric Practice
The article presents a clinical case of a multi-component infection in 8-year-old child. It is shown that on the background of the progress of infection (infection with Mycobacterium tuberculosis) typical, classic cyclic...