Evaluating the Results of Trabeculectomy with Collagen Matrix Compared with Mitomycin C and Trabeculectomy without Adjuvant in Patients with Open-Angle Glaucoma
Journal Title: PARIPEX-Indian Journal of Research - Year 2015, Vol 4, Issue 5
Abstract
Trabeculectomy is a standard method for patients with glaucoma with uncontrollable intraocular pressure (IOP). Biodegradable collagen matrix implant (Ologen) by changing the pattern of cell migration reduces the formation of scar tissue and increasing the success rate of surgery.In a randomized clinical trial, 60 patients with chronic open-angle glaucoma undergoing trabeculectomy surgery, were randomly assigned to one of the 3 groups, group 1 used Ologen implants, group 2 used mitomycin C and group 3 used no adjuvant. IOP and other results after trabeculectomy were studied in time intervals after operation. in this study, Ologen was an effective method in reducing intraocular pressure and reducing the number of anti-glaucoma drug therapies.
Authors and Affiliations
Dr. Rana Sorkhabi, Dr. Ali Mahdavi Fard, Dr. Zahra Poursayed, Dr. Mohammad Veshagh
Keywords
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